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SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans.
Chae H, Augustin R, Gatineau E, Mayoux E, Bensellam M, Antoine N, Khattab F, Lai BK, Brusa D, Stierstorfer B, Klein H, Singh B, Ruiz L, Pieper M, Mark M, Herrera PL, Gribble FM, Reimann F, Wojtusciszyn A, Broca C, Rita N, Piemonti L, Gilon P. Chae H, et al. Among authors: ruiz l. Mol Metab. 2020 Dec;42:101071. doi: 10.1016/j.molmet.2020.101071. Epub 2020 Sep 5. Mol Metab. 2020. PMID: 32896668 Free PMC article.
Modelling indoor radical chemistry during the HOMEChem campaign.
Østerstrøm FF, Carter TJ, Shaw DR, Abbatt JPD, Abeleira A, Arata C, Bottorff BP, Cardoso-Saldaña FJ, DeCarlo PF, Farmer DK, Goldstein AH, Ruiz LH, Kahan TF, Mattila JM, Novoselac A, Stevens PS, Reidy E, Rosales CMF, Wang C, Zhou S, Carslaw N. Østerstrøm FF, et al. Among authors: ruiz lh. Environ Sci Process Impacts. 2024 Dec 17. doi: 10.1039/d4em00628c. Online ahead of print. Environ Sci Process Impacts. 2024. PMID: 39688182
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.
Valdecantos MP, Ruiz L, Folgueira C, Rada P, Gomez-Santos B, Solas M, Hitos AB, Field J, Francisco V, Escalona-Garrido C, Zagmutt S, Calderon-Dominguez M, Mera P, Garcia-Martinez I, Maymó-Masip E, Grajales D, Alen R, Mora A, Sáinz N, Vides-Urrestarazu I, Vilarrasa N, Arbones-Mainar JM, Zaragoza C, Moreno-Aliaga MJ, Aspichueta P, Fernández-Veledo S, Vendrell J, Serra D, Herrero L, Schreiber R, Zechner R, Sabio G, Hornigold D, Rondinone CM, Jermutus L, Grimsby J, Valverde ÁM. Valdecantos MP, et al. Among authors: ruiz l. Nat Commun. 2024 Nov 28;15(1):10342. doi: 10.1038/s41467-024-54080-w. Nat Commun. 2024. PMID: 39609390 Free PMC article.
Angiotensin-converting enzyme 2 activation attenuates inflammation and oxidative stress in brain death donor followed by rat lung transplantation.
Oliveira-Melo P, Nepomuceno NA, Ruiz LM, Correia AT, Vilela VS, de Oliveira Braga KA, Manzuti GM, Feitosa DDM, Kennedy-Feitosa E, Wang A, Cypel M, Fernandes PMP. Oliveira-Melo P, et al. Among authors: ruiz lm. Sci Rep. 2024 Oct 9;14(1):23567. doi: 10.1038/s41598-024-75043-7. Sci Rep. 2024. PMID: 39384890 Free PMC article.
977 results