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Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR, Decout A, Glück S, Cavadini S, Makasheva K, Hovius R, Kempf G, Weiss J, Kozicka Z, Guey B, Melenec P, Fierz B, Thomä NH, Ablasser A. Pathare GR, et al. Among authors: ablasser a. Nature. 2020 Nov;587(7835):668-672. doi: 10.1038/s41586-020-2750-6. Epub 2020 Sep 10. Nature. 2020. PMID: 32911482
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: ablasser a. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
ReGLUation of cGAS.
Ablasser A. Ablasser A. Nat Immunol. 2016 Apr;17(4):347-9. doi: 10.1038/ni.3397. Nat Immunol. 2016. PMID: 27002833 No abstract available.
The role of cGAS in innate immunity and beyond.
Ablasser A, Gulen MF. Ablasser A, et al. J Mol Med (Berl). 2016 Oct;94(10):1085-1093. doi: 10.1007/s00109-016-1423-2. Epub 2016 May 6. J Mol Med (Berl). 2016. PMID: 27154323 Review.
Signalling strength determines proapoptotic functions of STING.
Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w. Nat Commun. 2017. PMID: 28874664 Free PMC article.
Targeting STING with covalent small-molecule inhibitors.
Haag SM, Gulen MF, Reymond L, Gibelin A, Abrami L, Decout A, Heymann M, van der Goot FG, Turcatti G, Behrendt R, Ablasser A. Haag SM, et al. Among authors: ablasser a. Nature. 2018 Jul;559(7713):269-273. doi: 10.1038/s41586-018-0287-8. Epub 2018 Jul 4. Nature. 2018. PMID: 29973723
60 results