Chen Y - Search Results

1

Synthetic vitamin K analogs inhibit inflammation by targeting the NLRP3 inflammasome.

Zheng X, Hou Y, He H, Chen Y, Zhou R, Wang X, Gong T, Jiang W. Zheng X, et al. Among authors: chen y. Cell Mol Immunol. 2021 Oct;18(10):2422-2430. doi: 10.1038/s41423-020-00545-z. Epub 2020 Sep 11. Cell Mol Immunol. 2021. PMID: 32917982 Free PMC article.

2

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders.

Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W, Deng X, Zhou R. Jiang H, et al. Among authors: chen y. J Exp Med. 2017 Nov 6;214(11):3219-3238. doi: 10.1084/jem.20171419. Epub 2017 Oct 11. J Exp Med. 2017. PMID: 29021150 Free PMC article.

3

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.

Huang Y, Jiang H, Chen Y, Wang X, Yang Y, Tao J, Deng X, Liang G, Zhang H, Jiang W, Zhou R. Huang Y, et al. Among authors: chen y. EMBO Mol Med. 2018 Apr;10(4):e8689. doi: 10.15252/emmm.201708689. EMBO Mol Med. 2018. PMID: 29531021 Free PMC article.

4

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.

He H, Jiang H, Chen Y, Ye J, Wang A, Wang C, Liu Q, Liang G, Deng X, Jiang W, Zhou R. He H, et al. Among authors: chen y. Nat Commun. 2018 Jun 29;9(1):2550. doi: 10.1038/s41467-018-04947-6. Nat Commun. 2018. PMID: 29959312 Free PMC article.

5

Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors.

Chen Y, He H, Jiang H, Li L, Hu Z, Huang H, Xu Q, Zhou R, Deng X. Chen Y, et al. Bioorg Med Chem Lett. 2020 Apr 1;30(7):127021. doi: 10.1016/j.bmcl.2020.127021. Epub 2020 Feb 6. Bioorg Med Chem Lett. 2020. PMID: 32057583

6

RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.

Chen Y, He H, Lin B, Chen Y, Deng X, Jiang W, Zhou R. Chen Y, et al. Cell Mol Immunol. 2021 Jun;18(6):1425-1436. doi: 10.1038/s41423-021-00683-y. Epub 2021 May 10. Cell Mol Immunol. 2021. PMID: 33972740 Free PMC article.

7

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.

Chen Y, Ruan ZR, Wang Y, Huang Q, Xue MQ, Zhou XL, Wang ED. Chen Y, et al. Nucleic Acids Res. 2018 Apr 20;46(7):3643-3656. doi: 10.1093/nar/gky211. Nucleic Acids Res. 2018. PMID: 29579307 Free PMC article.

8

Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex.

Zhou XL, Chen Y, Zeng QY, Ruan ZR, Fang P, Wang ED. Zhou XL, et al. Among authors: chen y. Nucleic Acids Res. 2019 Sep 19;47(16):8662-8674. doi: 10.1093/nar/gkz588. Nucleic Acids Res. 2019. PMID: 31287872 Free PMC article.

9

Translational Quality Control by Bacterial Threonyl-tRNA Synthetases.

Zhou XL, Chen Y, Fang ZP, Ruan ZR, Wang Y, Liu RJ, Xue MQ, Wang ED. Zhou XL, et al. Among authors: chen y. J Biol Chem. 2016 Sep 30;291(40):21208-21221. doi: 10.1074/jbc.M116.740472. Epub 2016 Aug 19. J Biol Chem. 2016. PMID: 27542414 Free PMC article.

10

Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity.

Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J. Wang QW, et al. Among authors: chen yf, chen y. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31438-31447. doi: 10.1073/pnas.2016416117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229564 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

180,640 results

Search Page

Filters