Pottie IR - Search Results

1

Imaging Butyrylcholinesterase in Multiple Sclerosis.

Thorne MWD, Cash MK, Reid GA, Burley DE, Luke D, Pottie IR, Darvesh S. Thorne MWD, et al. Among authors: pottie ir. Mol Imaging Biol. 2021 Feb;23(1):127-138. doi: 10.1007/s11307-020-01540-6. Epub 2020 Sep 14. Mol Imaging Biol. 2021. PMID: 32926288

2

Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants.

Darvesh S, Pottie IR, Darvesh KV, McDonald RS, Walsh R, Conrad S, Penwell A, Mataija D, Martin E. Darvesh S, et al. Among authors: pottie ir. Bioorg Med Chem. 2010 Mar 15;18(6):2232-2244. doi: 10.1016/j.bmc.2010.01.066. Epub 2010 Feb 4. Bioorg Med Chem. 2010. PMID: 20181484

3

Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase.

Macdonald IR, Reid GA, Joy EE, Pottie IR, Matte G, Burrell S, Mawko G, Martin E, Darvesh S. Macdonald IR, et al. Among authors: pottie ir. Mol Imaging Biol. 2011 Dec;13(6):1250-61. doi: 10.1007/s11307-010-0448-0. Mol Imaging Biol. 2011. PMID: 20976626

4

Thioesters for the in vitro evaluation of agents to image brain cholinesterases.

Macdonald IR, Jollymore CT, Reid GA, Pottie IR, Martin E, Darvesh S. Macdonald IR, et al. Among authors: pottie ir. J Enzyme Inhib Med Chem. 2013 Jun;28(3):447-55. doi: 10.3109/14756366.2011.647008. Epub 2012 Jan 11. J Enzyme Inhib Med Chem. 2013. PMID: 22233541 Free article.

5

Cysteine thioesters as myelin proteolipid protein analogues to examine the role of butyrylcholinesterase in myelin decompaction.

Pottie IR, Higgins EA, Blackman RA, Macdonald IR, Martin E, Darvesh S. Pottie IR, et al. ACS Chem Neurosci. 2011 Mar 16;2(3):151-9. doi: 10.1021/cn100090g. Epub 2010 Dec 30. ACS Chem Neurosci. 2011. PMID: 22778864 Free PMC article.

6

Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology.

Macdonald IR, Reid GA, Pottie IR, Martin E, Darvesh S. Macdonald IR, et al. Among authors: pottie ir. J Nucl Med. 2016 Feb;57(2):297-302. doi: 10.2967/jnumed.115.162032. Epub 2015 Nov 5. J Nucl Med. 2016. PMID: 26541777 Free article.

7

Development of acetophenone ligands as potential neuroimaging agents for cholinesterases.

Jollymore-Hughes CT, Pottie IR, Martin E, Rosenberry TL, Darvesh S. Jollymore-Hughes CT, et al. Among authors: pottie ir. Bioorg Med Chem. 2016 Nov 1;24(21):5270-5279. doi: 10.1016/j.bmc.2016.08.048. Epub 2016 Aug 28. Bioorg Med Chem. 2016. PMID: 27637382

8

Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease.

DeBay DR, Reid GA, Pottie IR, Martin E, Bowen CV, Darvesh S. DeBay DR, et al. Among authors: pottie ir. Alzheimers Dement (N Y). 2017 Feb 24;3(2):166-176. doi: 10.1016/j.trci.2017.01.005. eCollection 2017 Jun. Alzheimers Dement (N Y). 2017. PMID: 29067326 Free PMC article.

9

1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies.

Zueva IV, Lushchekina SV, Pottie IR, Darvesh S, Masson P. Zueva IV, et al. Among authors: pottie ir. Biomolecules. 2020 Nov 27;10(12):1608. doi: 10.3390/biom10121608. Biomolecules. 2020. PMID: 33260981 Free PMC article.

10

2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease.

Forrestall KL, Burley DE, Cash MK, Pottie IR, Darvesh S. Forrestall KL, et al. Among authors: pottie ir. Chem Biol Interact. 2021 Feb 1;335:109348. doi: 10.1016/j.cbi.2020.109348. Epub 2020 Dec 2. Chem Biol Interact. 2021. PMID: 33278462 Free PMC article.

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