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Page 1
ARGX-117, a therapeutic complement inhibiting antibody targeting C2.
Van de Walle I, Silence K, Budding K, Van de Ven L, Dijkxhoorn K, de Zeeuw E, Yildiz C, Gabriels S, Percier JM, Wildemann J, Meeldijk J, Simons PJ, Boon L, Cox L, Holgate R, Urbanus R, Otten HG, Leusen JHW, Blanchetot C, de Haard H, Hack CE, Boross P. Van de Walle I, et al. Among authors: hack ce. J Allergy Clin Immunol. 2021 Apr;147(4):1420-1429.e7. doi: 10.1016/j.jaci.2020.08.028. Epub 2020 Sep 11. J Allergy Clin Immunol. 2021. PMID: 32926878 Free PMC article.
Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy.
Budding K, Johansen LE, Van de Walle I, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, Bos JW, Jansen MD, Curial CAD, Silence K, de Haard H, Blanchetot C, Van de Ven L, Leusen JHW, Pasterkamp RJ, van den Berg LH, Hack CE, Boross P, van der Pol WL. Budding K, et al. Among authors: hack ce. Neurol Neuroimmunol Neuroinflamm. 2021 Nov 10;9(1):e1107. doi: 10.1212/NXI.0000000000001107. Print 2022 Jan. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 34759020 Free PMC article.
A novel proinflammatory role for granzyme A.
van Eck JA, Shan L, Meeldijk J, Hack CE, Bovenschen N. van Eck JA, et al. Among authors: hack ce. Cell Death Dis. 2017 Feb 23;8(2):e2630. doi: 10.1038/cddis.2017.56. Cell Death Dis. 2017. PMID: 28230859 Free PMC article. No abstract available.
A Promoter Polymorphism in the CD59 Complement Regulatory Protein Gene in Donor Lungs Correlates With a Higher Risk for Chronic Rejection After Lung Transplantation.
Budding K, van de Graaf EA, Kardol-Hoefnagel T, Broen JC, Kwakkel-van Erp JM, Oudijk EJ, van Kessel DA, Hack CE, Otten HG. Budding K, et al. Among authors: hack ce. Am J Transplant. 2016 Mar;16(3):987-98. doi: 10.1111/ajt.13497. Epub 2015 Oct 30. Am J Transplant. 2016. PMID: 26517734 Free article.
IgG antibodies in food allergy influence allergen-antibody complex formation and binding to B cells: a role for complement receptors.
Meulenbroek LA, de Jong RJ, den Hartog Jager CF, Monsuur HN, Wouters D, Nauta AJ, Knippels LM, van Neerven RJ, Ruiter B, Leusen JH, Hack CE, Bruijnzeel-Koomen CA, Knulst AC, Garssen J, van Hoffen E. Meulenbroek LA, et al. Among authors: hack ce. J Immunol. 2013 Oct 1;191(7):3526-33. doi: 10.4049/jimmunol.1202398. Epub 2013 Aug 30. J Immunol. 2013. PMID: 23997216
558 results