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A computational model predicting disruption of blood vessel development.
Kleinstreuer N, Dix D, Rountree M, Baker N, Sipes N, Reif D, Spencer R, Knudsen T. Kleinstreuer N, et al. PLoS Comput Biol. 2013 Apr;9(4):e1002996. doi: 10.1371/journal.pcbi.1002996. Epub 2013 Apr 4. PLoS Comput Biol. 2013. PMID: 23592958 Free PMC article.
Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes.
Leung MC, Phuong J, Baker NC, Sipes NS, Klinefelter GR, Martin MT, McLaurin KW, Setzer RW, Darney SP, Judson RS, Knudsen TB. Leung MC, et al. Among authors: baker nc. Environ Health Perspect. 2016 Jul;124(7):1050-61. doi: 10.1289/ehp.1510385. Epub 2015 Dec 11. Environ Health Perspect. 2016. PMID: 26662846 Free PMC article.
We confirmed the known role of estrogen and androgen signaling pathways in rodent TDS, and importantly, broadened the list of molecular targets to include retinoic acid signaling, vascular remodeling proteins, G-protein coupled receptors (GPCRs), and cytochrome P450s. CITATION: L …
We confirmed the known role of estrogen and androgen signaling pathways in rodent TDS, and importantly, broadened the list of molecular targ …
Computational Model of Secondary Palate Fusion and Disruption.
Hutson MS, Leung MCK, Baker NC, Spencer RM, Knudsen TB. Hutson MS, et al. Among authors: baker nc. Chem Res Toxicol. 2017 Apr 17;30(4):965-979. doi: 10.1021/acs.chemrestox.6b00350. Epub 2017 Jan 20. Chem Res Toxicol. 2017. PMID: 28045533 Free PMC article.
Blood-brain barrier development: Systems modeling and predictive toxicology.
Saili KS, Zurlinden TJ, Schwab AJ, Silvin A, Baker NC, Hunter ES 3rd, Ginhoux F, Knudsen TB. Saili KS, et al. Among authors: baker nc. Birth Defects Res. 2017 Dec 1;109(20):1680-1710. doi: 10.1002/bdr2.1180. Birth Defects Res. 2017. PMID: 29251840 Free PMC article. Review.
Building a developmental toxicity ontology.
Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G. Baker N, et al. Birth Defects Res. 2018 Apr 3;110(6):502-518. doi: 10.1002/bdr2.1189. Epub 2018 Jan 31. Birth Defects Res. 2018. PMID: 29383852 Review.
Systems Modeling of Developmental Vascular Toxicity.
Saili KS, Franzosa JA, Baker NC, Ellis-Hutchings RG, Settivari RS, Carney EW, Spencer R, Zurlinden TJ, Kleinstreuer NC, Li S, Xia M, Knudsen TB. Saili KS, et al. Among authors: baker nc. Curr Opin Toxicol. 2019 Jun 1;15(1):55-63. doi: 10.1016/j.cotox.2019.04.004. Curr Opin Toxicol. 2019. PMID: 32030360 Free PMC article.
95 results