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FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF, Kang W. Zhang J, et al. Among authors: chan mwy, chan rck. Oncogene. 2020 Oct;39(43):6647-6663. doi: 10.1038/s41388-020-01458-x. Epub 2020 Sep 15. Oncogene. 2020. PMID: 32934314 Free PMC article.
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway.
Kang W, Zhang J, Huang T, Zhou Y, Wong CC, Chan RCK, Dong Y, Wu F, Zhang B, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF. Kang W, et al. Among authors: chan mwy, chan rck. Oncogene. 2021 Mar;40(9):1578-1594. doi: 10.1038/s41388-020-01579-3. Epub 2021 Jan 15. Oncogene. 2021. PMID: 33452458 Free PMC article.
STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker.
Chen B, Chan WN, Mui CW, Liu X, Zhang J, Wang Y, Cheung AHK, Chan AKY, Chan RCK, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, Wong CC, Wu WKK, Cheng ASL, Yu J, Lo KW, To KF, Kang W. Chen B, et al. Among authors: chan aky, chan rck, chan wn. Mol Cancer. 2021 Nov 12;20(1):147. doi: 10.1186/s12943-021-01451-2. Mol Cancer. 2021. PMID: 34772410 Free PMC article. No abstract available.
560 results