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Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.
Kent OA, Saha M, Coyaud E, Burston HE, Law N, Dadson K, Chen S, Laurent EM, St-Germain J, Sun RX, Matsumoto Y, Cowen J, Montgomery-Song A, Brown KR, Ishak C, Rose J, De Carvalho DD, He HH, Raught B, Billia F, Kannu P, Rottapel R. Kent OA, et al. Nat Commun. 2020 Sep 16;11(1):4673. doi: 10.1038/s41467-020-18483-9. Nat Commun. 2020. PMID: 32938917 Free PMC article.
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.
Cullis J, Meiri D, Sandi MJ, Radulovich N, Kent OA, Medrano M, Mokady D, Normand J, Larose J, Marcotte R, Marshall CB, Ikura M, Ketela T, Moffat J, Neel BG, Gingras AC, Tsao MS, Rottapel R. Cullis J, et al. Among authors: kent oa. Cancer Cell. 2014 Feb 10;25(2):181-95. doi: 10.1016/j.ccr.2014.01.025. Cancer Cell. 2014. PMID: 24525234 Free article.
Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.
Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, Moran MF, Grynpas MD, Wrana JL, Superti-Furga G, Koleske AJ, Pendergast AM, Rottapel R. Matsumoto Y, et al. Among authors: kent oa. J Clin Invest. 2016 Dec 1;126(12):4482-4496. doi: 10.1172/JCI87802. Epub 2016 Oct 31. J Clin Invest. 2016. PMID: 27797343 Free PMC article.
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis.
Chaulk SG, Thede GL, Kent OA, Xu Z, Gesner EM, Veldhoen RA, Khanna SK, Goping IS, MacMillan AM, Mendell JT, Young HS, Fahlman RP, Glover JN. Chaulk SG, et al. Among authors: kent oa. RNA Biol. 2011 Nov-Dec;8(6):1105-14. doi: 10.4161/rna.8.6.17410. Epub 2011 Nov 1. RNA Biol. 2011. PMID: 21955497
33 results