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Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19.
Mann ER, Menon M, Knight SB, Konkel JE, Jagger C, Shaw TN, Krishnan S, Rattray M, Ustianowski A, Bakerly ND, Dark P, Lord G, Simpson A, Felton T, Ho LP; NIHR Respiratory TRC,; Feldmann M; CIRCO,; Grainger JR, Hussell T. Mann ER, et al. Among authors: dark p. Sci Immunol. 2020 Sep 17;5(51):eabd6197. doi: 10.1126/sciimmunol.abd6197. Sci Immunol. 2020. PMID: 32943497 Free PMC article.
'In a dark place, we find ourselves': light intensity in critical care units.
Durrington HJ, Clark R, Greer R, Martial FP, Blaikley J, Dark P, Lucas RJ, Ray DW. Durrington HJ, et al. Among authors: dark p. Intensive Care Med Exp. 2017 Dec;5(1):9. doi: 10.1186/s40635-017-0122-9. Epub 2017 Feb 7. Intensive Care Med Exp. 2017. PMID: 28168516 Free PMC article.
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example.
Overton CE, Stage HB, Ahmad S, Curran-Sebastian J, Dark P, Das R, Fearon E, Felton T, Fyles M, Gent N, Hall I, House T, Lewkowicz H, Pang X, Pellis L, Sawko R, Ustianowski A, Vekaria B, Webb L. Overton CE, et al. Among authors: dark p. Infect Dis Model. 2020 Jul 4;5:409-441. doi: 10.1016/j.idm.2020.06.008. eCollection 2020. Infect Dis Model. 2020. PMID: 32691015 Free PMC article.
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, Wiselka M, Ustianowski A, Elmahi E, Prudon B, Whitehouse T, Felton T, Williams J, Faccenda J, Underwood J, Baillie JK, Chappell LC, Faust SN, Jaki T, Jeffery K, Lim WS, Montgomery A, Rowan K, Tarning J, Watson JA, White NJ, Juszczak E, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2020 Nov 19;383(21):2030-2040. doi: 10.1056/NEJMoa2022926. Epub 2020 Oct 8. N Engl J Med. 2020. PMID: 33031652 Free PMC article. Clinical Trial.
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.
Thwaites RS, Sanchez Sevilla Uruchurtu A, Siggins MK, Liew F, Russell CD, Moore SC, Fairfield C, Carter E, Abrams S, Short CE, Thaventhiran T, Bergstrom E, Gardener Z, Ascough S, Chiu C, Docherty AB, Hunt D, Crow YJ, Solomon T, Taylor GP, Turtle L, Harrison EM, Dunning J, Semple MG, Baillie JK, Openshaw PJ; ISARIC4C investigators. Thwaites RS, et al. Sci Immunol. 2021 Mar 10;6(57):eabg9873. doi: 10.1126/sciimmunol.abg9873. Sci Immunol. 2021. PMID: 33692097 Free PMC article.
Alterations in T and B cell function persist in convalescent COVID-19 patients.
Shuwa HA, Shaw TN, Knight SB, Wemyss K, McClure FA, Pearmain L, Prise I, Jagger C, Morgan DJ, Khan S, Brand O, Mann ER, Ustianowski A, Bakerly ND, Dark P, Brightling CE, Brij S; CIRCO; Felton T, Simpson A, Grainger JR, Hussell T, Konkel JE, Menon M. Shuwa HA, et al. Among authors: dark p. Med. 2021 Jun 11;2(6):720-735.e4. doi: 10.1016/j.medj.2021.03.013. Epub 2021 Mar 31. Med. 2021. PMID: 33821250 Free PMC article.
262 results