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Affinity proteomic dissection of the human nuclear cap-binding complex interactome.
Dou Y, Kalmykova S, Pashkova M, Oghbaie M, Jiang H, Molloy KR, Chait BT, Rout MP, Fenyö D, Jensen TH, Altukhov I, LaCava J. Dou Y, et al. Among authors: lacava j. Nucleic Acids Res. 2020 Oct 9;48(18):10456-10469. doi: 10.1093/nar/gkaa743. Nucleic Acids Res. 2020. PMID: 32960270 Free PMC article.
Cancer cells co-evolve with retrotransposons to mitigate viral mimicry.
Sun S, Hong J, You E, Tsanov KM, Chacon-Barahona J, Gioacchino AD, Hoyos D, Li H, Jiang H, Ly H, Marhon S, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. Among authors: lacava j. bioRxiv [Preprint]. 2023 May 20:2023.05.19.541456. doi: 10.1101/2023.05.19.541456. bioRxiv. 2023. PMID: 37292765 Free PMC article. Preprint.
The human cap-binding complex is functionally connected to the nuclear RNA exosome.
Andersen PR, Domanski M, Kristiansen MS, Storvall H, Ntini E, Verheggen C, Schein A, Bunkenborg J, Poser I, Hallais M, Sandberg R, Hyman A, LaCava J, Rout MP, Andersen JS, Bertrand E, Jensen TH. Andersen PR, et al. Among authors: lacava j. Nat Struct Mol Biol. 2013 Dec;20(12):1367-76. doi: 10.1038/nsmb.2703. Epub 2013 Nov 24. Nat Struct Mol Biol. 2013. PMID: 24270879 Free PMC article.
Rapid, optimized interactomic screening.
Hakhverdyan Z, Domanski M, Hough LE, Oroskar AA, Oroskar AR, Keegan S, Dilworth DJ, Molloy KR, Sherman V, Aitchison JD, Fenyö D, Chait BT, Jensen TH, Rout MP, LaCava J. Hakhverdyan Z, et al. Among authors: lacava j. Nat Methods. 2015 Jun;12(6):553-60. doi: 10.1038/nmeth.3395. Epub 2015 May 4. Nat Methods. 2015. PMID: 25938370 Free PMC article.
Characterization of L1-Ribonucleoprotein Particles.
Taylor MS, LaCava J, Dai L, Mita P, Burns KH, Rout MP, Boeke JD. Taylor MS, et al. Among authors: lacava j. Methods Mol Biol. 2016;1400:311-38. doi: 10.1007/978-1-4939-3372-3_20. Methods Mol Biol. 2016. PMID: 26895062 Free PMC article.
Optimized Affinity Capture of Yeast Protein Complexes.
LaCava J, Fernandez-Martinez J, Hakhverdyan Z, Rout MP. LaCava J, et al. Cold Spring Harb Protoc. 2016 Jul 1;2016(7). doi: 10.1101/pdb.prot087932. Cold Spring Harb Protoc. 2016. PMID: 27371596
91 results