Wilson AJ - Search Results

1

Selective Affimers Recognise the BCL-2 Family Proteins BCL-x_L and MCL-1 through Noncanonical Structural Motifs*.

Miles JA, Hobor F, Trinh CH, Taylor J, Tiede C, Rowell PR, Jackson BR, Nadat FA, Ramsahye P, Kyle HF, Wicky BIM, Clarke J, Tomlinson DC, Wilson AJ, Edwards TA. Miles JA, et al. Among authors: wilson aj. Chembiochem. 2021 Jan 5;22(1):232-240. doi: 10.1002/cbic.202000585. Epub 2020 Nov 2. Chembiochem. 2021. PMID: 32961017 Free PMC article.

2

N-alkylated oligoamide alpha-helical proteomimetics.

Campbell F, Plante JP, Edwards TA, Warriner SL, Wilson AJ. Campbell F, et al. Among authors: wilson aj. Org Biomol Chem. 2010 May 21;8(10):2344-51. doi: 10.1039/c001164a. Epub 2010 Mar 18. Org Biomol Chem. 2010. PMID: 20448891

3

Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction.

Plante JP, Burnley T, Malkova B, Webb ME, Warriner SL, Edwards TA, Wilson AJ. Plante JP, et al. Among authors: wilson aj. Chem Commun (Camb). 2009 Sep 14;(34):5091-3. doi: 10.1039/b908207g. Epub 2009 Jun 24. Chem Commun (Camb). 2009. PMID: 20448956 Free PMC article.

4

Helix-mediated protein--protein interactions as targets for intervention using foldamers.

Edwards TA, Wilson AJ. Edwards TA, et al. Among authors: wilson aj. Amino Acids. 2011 Aug;41(3):743-54. doi: 10.1007/s00726-011-0880-8. Epub 2011 Mar 17. Amino Acids. 2011. PMID: 21409387 Review.

5

2-O-alkylated para-benzamide α-helix mimetics: the role of scaffold curvature.

Azzarito V, Prabhakaran P, Bartlett AI, Murphy NS, Hardie MJ, Kilner CA, Edwards TA, Warriner SL, Wilson AJ. Azzarito V, et al. Among authors: wilson aj. Org Biomol Chem. 2012 Aug 28;10(32):6469-72. doi: 10.1039/c2ob26262b. Epub 2012 Jul 11. Org Biomol Chem. 2012. PMID: 22785578

6

Modeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable.

Fuller JC, Jackson RM, Edwards TA, Wilson AJ, Shirts MR. Fuller JC, et al. Among authors: wilson aj. PLoS One. 2012;7(8):e43253. doi: 10.1371/journal.pone.0043253. Epub 2012 Aug 20. PLoS One. 2012. PMID: 22916232 Free PMC article.

7

Microwave assisted solid phase synthesis of highly functionalized N-alkylated oligobenzamide α-helix mimetics.

Long K, Edwards TA, Wilson AJ. Long K, et al. Among authors: wilson aj. Bioorg Med Chem. 2013 Jul 15;21(14):4034-40. doi: 10.1016/j.bmc.2012.09.053. Epub 2012 Oct 3. Bioorg Med Chem. 2013. PMID: 23117175 Free article.

8

Small-molecule proteomimetic inhibitors of the HIF-1α-p300 protein-protein interaction.

Burslem GM, Kyle HF, Breeze AL, Edwards TA, Nelson A, Warriner SL, Wilson AJ. Burslem GM, et al. Among authors: wilson aj. Chembiochem. 2014 May 26;15(8):1083-7. doi: 10.1002/cbic.201400009. Epub 2014 Apr 29. Chembiochem. 2014. PMID: 24782431 Free PMC article.

9

Orthogonal functionalisation of α-helix mimetics.

Barnard A, Long K, Yeo DJ, Miles JA, Azzarito V, Burslem GM, Prabhakaran P, A Edwards T, Wilson AJ. Barnard A, et al. Among authors: wilson aj. Org Biomol Chem. 2014 Sep 21;12(35):6794-9. doi: 10.1039/c4ob00915k. Org Biomol Chem. 2014. PMID: 25065821 Free PMC article.

10

Multivalent helix mimetics for PPI-inhibition.

Barnard A, Miles JA, Burslem GM, Barker AM, Wilson AJ. Barnard A, et al. Among authors: wilson aj. Org Biomol Chem. 2015 Jan 7;13(1):258-64. doi: 10.1039/c4ob02066a. Org Biomol Chem. 2015. PMID: 25408290 Free article.

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