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Page 1
[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity.
Rushworth JL, Thawani AR, Fajardo-Ruiz E, Meiring JCM, Heise C, White AJP, Akhmanova A, Brandt JR, Thorn-Seshold O, Fuchter MJ. Rushworth JL, et al. Among authors: thawani ar. JACS Au. 2022 Oct 19;2(11):2561-2570. doi: 10.1021/jacsau.2c00435. eCollection 2022 Nov 28. JACS Au. 2022. PMID: 36465552 Free PMC article.
Data-driven discovery of molecular photoswitches with multioutput Gaussian processes.
Griffiths RR, Greenfield JL, Thawani AR, Jamasb AR, Moss HB, Bourached A, Jones P, McCorkindale W, Aldrick AA, Fuchter MJ, Lee AA. Griffiths RR, et al. Among authors: thawani ar. Chem Sci. 2022 Nov 10;13(45):13541-13551. doi: 10.1039/d2sc04306h. eCollection 2022 Nov 23. Chem Sci. 2022. PMID: 36507171 Free PMC article.
The conducting state of TRPA1 modulates channel lateral mobility.
Sampieri A, Padilla-Flores T, Thawani AR, Lam PY, Fuchter MJ, Peterson R, Vaca L. Sampieri A, et al. Among authors: thawani ar. Cell Calcium. 2023 Dec;116:102800. doi: 10.1016/j.ceca.2023.102800. Epub 2023 Sep 18. Cell Calcium. 2023. PMID: 37776645
Optimization of a Series of RIPK2 PROTACs.
Miah AH, Smith IED, Rackham M, Mares A, Thawani AR, Nagilla R, Haile PA, Votta BJ, Gordon LJ, Watt G, Denyer J, Fisher DT, Dace P, Giffen P, Goncalves A, Churcher I, Scott-Stevens P, Harling JD. Miah AH, et al. Among authors: thawani ar. J Med Chem. 2021 Sep 9;64(17):12978-13003. doi: 10.1021/acs.jmedchem.1c01118. Epub 2021 Aug 25. J Med Chem. 2021. PMID: 34432979
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.
Mares A, Miah AH, Smith IED, Rackham M, Thawani AR, Cryan J, Haile PA, Votta BJ, Beal AM, Capriotti C, Reilly MA, Fisher DT, Zinn N, Bantscheff M, MacDonald TT, Vossenkamper A, Dace P, Churcher I, Benowitz AB, Watt G, Denyer J, Scott-Stevens P, Harling JD. Mares A, et al. Among authors: thawani ar. Commun Biol. 2020 Mar 20;3(1):140. doi: 10.1038/s42003-020-0868-6. Commun Biol. 2020. PMID: 32198438 Free PMC article.