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Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma.
Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I, Kipnis J. Cugurra A, et al. Among authors: schuettpelz lg. Science. 2021 Jul 23;373(6553):eabf7844. doi: 10.1126/science.abf7844. Epub 2021 Jun 3. Science. 2021. PMID: 34083447 Free PMC article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Among authors: schuettpelz lg. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice.
Schmitt EG, Toth KA, Risma SI, Kolicheski A, Saucier N, Berríos RJF, Greenberg ZJ, Leiding JW, Bleesing JJ, Thatayatikom A, Schuettpelz LG, Edwards JR, Vogel TP, Cooper MA. Schmitt EG, et al. Among authors: schuettpelz lg. JCI Insight. 2022 Nov 8;7(21):e162695. doi: 10.1172/jci.insight.162695. JCI Insight. 2022. PMID: 36136607 Free PMC article.
39 results