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Page 1
Characterization of Apo-Form Selective Inhibition of Indoleamine 2,3-Dioxygenase*.
Ortiz-Meoz RF, Wang L, Matico R, Rutkowska-Klute A, De la Rosa M, Bedard S, Midgett R, Strohmer K, Thomson D, Zhang C, Mebrahtu M, Guss J, Totoritis R, Consler T, Campobasso N, Taylor D, Lewis T, Weaver K, Muelbaier M, Seal J, Dunham R, Kazmierski W, Favre D, Bergamini G, Shewchuk L, Rendina A, Zhang G. Ortiz-Meoz RF, et al. Among authors: dunham r. Chembiochem. 2021 Feb 2;22(3):516-522. doi: 10.1002/cbic.202000298. Epub 2020 Nov 16. Chembiochem. 2021. PMID: 32974990
DNA-Encoded Library Technology-Based Discovery, Lead Optimization, and Prodrug Strategy toward Structurally Unique Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors.
Kazmierski WM, Xia B, Miller J, De la Rosa M, Favre D, Dunham RM, Washio Y, Zhu Z, Wang F, Mebrahtu M, Deng H, Basilla J, Wang L, Evindar G, Fan L, Olszewski A, Prabhu N, Davie C, Messer JA, Samano V. Kazmierski WM, et al. J Med Chem. 2020 Apr 9;63(7):3552-3562. doi: 10.1021/acs.jmedchem.9b01799. Epub 2020 Mar 19. J Med Chem. 2020. PMID: 32073266
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.
Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, De C, Wills SR, Falcinelli SD, Galardi C, Walum H, Schramm NJ, Deutsch J, Lifson JD, Fennessey CM, Keele BF, Jean S, Maguire S, Liao B, Browne EP, Ferris RG, Brehm JH, Favre D, Vanderford TH, Bosinger SE, Jones CD, Routy JP, Archin NM, Margolis DM, Wahl A, Dunham RM, Silvestri G, Chahroudi A, Garcia JV. Nixon CC, et al. Among authors: dunham rm. Nature. 2020 Feb;578(7793):160-165. doi: 10.1038/s41586-020-1951-3. Epub 2020 Jan 22. Nature. 2020. PMID: 31969707 Free PMC article.
Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques.
Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM. Vujkovic-Cvijin I, et al. Among authors: dunham rm. Cell Rep. 2015 Nov 24;13(8):1589-97. doi: 10.1016/j.celrep.2015.10.026. Epub 2015 Nov 12. Cell Rep. 2015. PMID: 26586432 Free PMC article.
Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
Bricker KM, Obregon-Perko V, Williams B, Oliver D, Uddin F, Neja M, Hopkins L, Dashti A, Jean S, Wood JS, Ehnert S, Liang S, Vanderford T, Tharp GK, Bosinger SE, Schauer AP, Mavigner M, Cottrell ML, Margolis D, Dunham RM, Chahroudi A. Bricker KM, et al. J Virol. 2022 Apr 13;96(7):e0169921. doi: 10.1128/jvi.01699-21. Epub 2022 Mar 16. J Virol. 2022. PMID: 35293766 Free PMC article.
Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, Baker C, Kuruc JD, Gay CL, James LI, Wu G, Zuck P, Rioja I, Furze RC, Prinjha RK, Howell BJ, Swanstrom R, Browne EP, Strahl BD, Dunham RM, Archin NM, Margolis DM. Falcinelli SD, et al. Among authors: dunham rm. J Clin Invest. 2022 Apr 15;132(8):e157281. doi: 10.1172/JCI157281. J Clin Invest. 2022. PMID: 35426377 Free PMC article.
Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.
Engram JC, Dunham RM, Makedonas G, Vanderford TH, Sumpter B, Klatt NR, Ratcliffe SJ, Garg S, Paiardini M, McQuoid M, Altman JD, Staprans SI, Betts MR, Garber DA, Feinberg MB, Silvestri G. Engram JC, et al. Among authors: dunham rm. J Immunol. 2009 Jul 1;183(1):706-17. doi: 10.4049/jimmunol.0803746. J Immunol. 2009. PMID: 19542473
Cell-cycle dysregulation in the immunopathogenesis of AIDS.
Paiardini M, Cervasi B, Dunham R, Sumpter B, Radziewicz H, Silvestri G. Paiardini M, et al. Among authors: dunham r. Immunol Res. 2004;29(1-3):253-68. doi: 10.1385/IR:29:1-3:253. Immunol Res. 2004. PMID: 15181287 Review.
220 results