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An Epigenetic Mechanism Underlying Chromosome 17p Deletion-Driven Tumorigenesis.
Chen M, Chen X, Li S, Pan X, Gong Y, Zheng J, Xu J, Zhao C, Zhang Q, Zhang S, Qi L, Wang Z, Shi K, Ding BS, Xue Z, Chen L, Yang S, Wang Y, Niu T, Dai L, Lowe SW, Chen C, Liu Y. Chen M, et al. Among authors: chen l, chen c, chen x. Cancer Discov. 2021 Jan;11(1):194-207. doi: 10.1158/2159-8290.CD-20-0336. Epub 2020 Sep 25. Cancer Discov. 2021. PMID: 32978226 Free PMC article.
Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma.
Wang X, Zhou R, Xiong Y, Zhou L, Yan X, Wang M, Li F, Xie C, Zhang Y, Huang Z, Ding C, Shi K, Li W, Liu Y, Cao Z, Zhang ZN, Zhou S, Chen C, Zhang Y, Chen L, Wang Y. Wang X, et al. Among authors: chen l, chen c. Cell Res. 2021 Jun;31(6):684-702. doi: 10.1038/s41422-020-00451-z. Epub 2021 Jan 4. Cell Res. 2021. PMID: 33390587 Free PMC article.
Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: chen z, chen l, chen c, chen s, chen h. Nature. 2021 Feb;590(7844):E23. doi: 10.1038/s41586-020-03108-4. Nature. 2021. PMID: 33469221 No abstract available.
Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis.
Zhang H, Ma Y, Cheng X, Wu D, Huang X, Chen B, Ren Y, Jiang W, Tang X, Bai T, Chen Y, Zhao Y, Zhang C, Xiao X, Liu J, Deng Y, Ye T, Chen L, Liu HM, Friedman SL, Chen L, Ding BS, Cao Z. Zhang H, et al. Among authors: chen l, chen b, chen y. Sci Transl Med. 2021 Oct 6;13(614):eabd1206. doi: 10.1126/scitranslmed.abd1206. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613814
Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer.
Zhang L, Zhang Y, Wang C, Yang Y, Ni Y, Wang Z, Song T, Yao M, Liu Z, Chao N, Yang Y, Shao J, Li Z, Zhou R, Chen L, Zhang D, Zhao Y, Liu W, Li Y, He P, Lin JW, Wang Y, Zhang K, Chen L, Li W. Zhang L, et al. Among authors: chen l. Signal Transduct Target Ther. 2022 Jan 14;7(1):9. doi: 10.1038/s41392-021-00824-9. Signal Transduct Target Ther. 2022. PMID: 35027529 Free PMC article.
Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells.
Hong W, Yang J, Zou J, Bi Z, He C, Lei H, He X, Li X, Alu A, Ren W, Wang Z, Jiang X, Zhong K, Jia G, Yang Y, Yu W, Huang Q, Yang M, Zhou Y, Zhao Y, Kuang D, Wang J, Wang H, Chen S, Luo M, Zhang Z, Lu T, Chen L, Que H, He Z, Sun Q, Wang W, Shen G, Lu G, Zhao Z, Yang L, Yang J, Wang Z, Li J, Song X, Dai L, Chen C, Geng J, Gou M, Chen L, Dong H, Peng Y, Huang C, Qian Z, Cheng W, Fan C, Wei Y, Su Z, Tong A, Lu S, Peng X, Wei X. Hong W, et al. Among authors: chen l, chen s, chen c. Cell Mol Immunol. 2022 May;19(5):577-587. doi: 10.1038/s41423-022-00845-6. Epub 2022 Mar 10. Cell Mol Immunol. 2022. PMID: 35273357 Free PMC article.
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming.
Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, Dai S, Zhang M, Wang Y, Wang B, Zheng J, Wang Y, Xu J, Wang J, Wu B, Chen M, Liu H, Xue J, Huang M, Gong Y, Zhu J, Zhou L, Zhang Y, Yu M, Tian P, Fan M, Lu Z, Xue Z, Zhao Y, Yang H, Zhao C, Wang Y, Han J, Yang S, Xie D, Chen L, Zhong Q, Zeng M, Lowe SW, Lu Y, Liu Y, Wei Y, Chen C. Na F, et al. Among authors: chen j, chen l, chen m, chen c, chen x. Nat Cancer. 2022 Jun;3(6):753-767. doi: 10.1038/s43018-022-00361-6. Epub 2022 Apr 21. Nat Cancer. 2022. PMID: 35449309 Free PMC article.
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