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Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.
Conway BR, O'Sullivan ED, Cairns C, O'Sullivan J, Simpson DJ, Salzano A, Connor K, Ding P, Humphries D, Stewart K, Teenan O, Pius R, Henderson NC, Bénézech C, Ramachandran P, Ferenbach D, Hughes J, Chandra T, Denby L. Conway BR, et al. Among authors: simpson dj. J Am Soc Nephrol. 2020 Dec;31(12):2833-2854. doi: 10.1681/ASN.2020060806. Epub 2020 Sep 25. J Am Soc Nephrol. 2020. PMID: 32978267 Free PMC article.
cGAS surveillance of micronuclei links genome instability to innate immunity.
Mackenzie KJ, Carroll P, Martin CA, Murina O, Fluteau A, Simpson DJ, Olova N, Sutcliffe H, Rainger JK, Leitch A, Osborn RT, Wheeler AP, Nowotny M, Gilbert N, Chandra T, Reijns MAM, Jackson AP. Mackenzie KJ, et al. Among authors: simpson dj. Nature. 2017 Aug 24;548(7668):461-465. doi: 10.1038/nature23449. Epub 2017 Jul 24. Nature. 2017. PMID: 28738408 Free PMC article.
Epigenetic age prediction.
Simpson DJ, Chandra T. Simpson DJ, et al. Aging Cell. 2021 Sep;20(9):e13452. doi: 10.1111/acel.13452. Epub 2021 Aug 20. Aging Cell. 2021. PMID: 34415665 Free PMC article. Review.
Cellular reprogramming and epigenetic rejuvenation.
Simpson DJ, Olova NN, Chandra T. Simpson DJ, et al. Clin Epigenetics. 2021 Sep 6;13(1):170. doi: 10.1186/s13148-021-01158-7. Clin Epigenetics. 2021. PMID: 34488874 Free PMC article. Review.
Probabilistic inference of epigenetic age acceleration from cellular dynamics.
Dabrowski JK, Yang EJ, Crofts SJC, Hillary RF, Simpson DJ, McCartney DL, Marioni RE, Kirschner K, Latorre-Crespo E, Chandra T. Dabrowski JK, et al. Among authors: simpson dj. Nat Aging. 2024 Oct;4(10):1493-1507. doi: 10.1038/s43587-024-00700-5. Epub 2024 Sep 23. Nat Aging. 2024. PMID: 39313745 Free PMC article.
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Among authors: simpson dj. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
173 results