Bengoa-Vergniory N - Search Results

1

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.

Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, Cragg S, Dehay B, Bitan G, Matute C, Bezard E, Wade-Martins R. Bengoa-Vergniory N, et al. Nat Commun. 2020 Sep 28;11(1):4885. doi: 10.1038/s41467-020-18689-x. Nat Commun. 2020. PMID: 32985503 Free PMC article.

2

Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy.

Wobst HJ, Denk F, Oliver PL, Livieratos A, Taylor TN, Knudsen MH, Bengoa-Vergniory N, Bannerman D, Wade-Martins R. Wobst HJ, et al. Sci Rep. 2017 Feb 24;7:43198. doi: 10.1038/srep43198. Sci Rep. 2017. PMID: 28233851 Free PMC article.

3

Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles.

Doucet M, El-Turabi A, Zabel F, Hunn BHM, Bengoa-Vergniory N, Cioroch M, Ramm M, Smith AM, Gomes AC, Cabral de Miranda G, Wade-Martins R, Bachmann MF. Doucet M, et al. PLoS One. 2017 Aug 10;12(8):e0181844. doi: 10.1371/journal.pone.0181844. eCollection 2017. PLoS One. 2017. PMID: 28797124 Free PMC article.

4

Alpha-synuclein oligomers: a new hope.

Bengoa-Vergniory N, Roberts RF, Wade-Martins R, Alegre-Abarrategui J. Bengoa-Vergniory N, et al. Acta Neuropathol. 2017 Dec;134(6):819-838. doi: 10.1007/s00401-017-1755-1. Epub 2017 Aug 12. Acta Neuropathol. 2017. PMID: 28803412 Free PMC article. Review.

5

Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo.

McMillan KJ, Murray TK, Bengoa-Vergniory N, Cordero-Llana O, Cooper J, Buckley A, Wade-Martins R, Uney JB, O'Neill MJ, Wong LF, Caldwell MA. McMillan KJ, et al. Mol Ther. 2017 Oct 4;25(10):2404-2414. doi: 10.1016/j.ymthe.2017.08.017. Epub 2017 Aug 31. Mol Ther. 2017. PMID: 28927576 Free PMC article.

6

Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease.

Ruffmann C, Bengoa-Vergniory N, Poggiolini I, Ritchie D, Hu MT, Alegre-Abarrategui J, Parkkinen L. Ruffmann C, et al. Neuropathol Appl Neurobiol. 2018 Dec;44(7):722-736. doi: 10.1111/nan.12486. Epub 2018 May 8. Neuropathol Appl Neurobiol. 2018. PMID: 29676021 Free PMC article.

7

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.

Zambon F, Cherubini M, Fernandes HJR, Lang C, Ryan BJ, Volpato V, Bengoa-Vergniory N, Vingill S, Attar M, Booth HDE, Haenseler W, Vowles J, Bowden R, Webber C, Cowley SA, Wade-Martins R. Zambon F, et al. Hum Mol Genet. 2019 Jun 15;28(12):2001-2013. doi: 10.1093/hmg/ddz038. Hum Mol Genet. 2019. PMID: 30753527 Free PMC article.

8

Alpha-Synuclein Proximity Ligation Assay (AS-PLA) in Brain Sections to Probe for Alpha-Synuclein Oligomers.

Roberts RF, Bengoa-Vergniory N, Alegre-Abarrategui J. Roberts RF, et al. Methods Mol Biol. 2019;1948:69-76. doi: 10.1007/978-1-4939-9124-2_7. Methods Mol Biol. 2019. PMID: 30771171 Free article.

9

Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior.

Hunn BHM, Vingill S, Threlfell S, Alegre-Abarrategui J, Magdelyns M, Deltheil T, Bengoa-Vergniory N, Oliver PL, Cioroch M, Doig NM, Bannerman DM, Cragg SJ, Wade-Martins R. Hunn BHM, et al. Cell Rep. 2019 Oct 22;29(4):920-931.e7. doi: 10.1016/j.celrep.2019.09.029. Cell Rep. 2019. PMID: 31644913 Free PMC article.

10

Targeting Alpha-Synuclein as a Therapy for Parkinson's Disease.

Fields CR, Bengoa-Vergniory N, Wade-Martins R. Fields CR, et al. Front Mol Neurosci. 2019 Dec 5;12:299. doi: 10.3389/fnmol.2019.00299. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31866823 Free PMC article. Review.

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