Brown LV - Search Results

1

De-risking clinical trial failure through mechanistic simulation.

Brown LV, Wagg J, Darley R, van Hateren A, Elliott T, Gaffney EA, Coles MC. Brown LV, et al. Immunother Adv. 2022 Aug 23;2(1):ltac017. doi: 10.1093/immadv/ltac017. eCollection 2022. Immunother Adv. 2022. PMID: 36176591 Free PMC article.

2

Analysis of cellular kinetic models suggest that physiologically based model parameters may be inherently, practically unidentifiable.

Brown LV, Coles MC, McConnell M, Ratushny AV, Gaffney EA. Brown LV, et al. J Pharmacokinet Pharmacodyn. 2022 Oct;49(5):539-556. doi: 10.1007/s10928-022-09819-7. Epub 2022 Aug 6. J Pharmacokinet Pharmacodyn. 2022. PMID: 35933452 Free PMC article.

3

Reactions of amines with ozone and chlorine: Two novel oxidative methods to evaluate the N-DBP formation potential from dissolved organic nitrogen.

Essaïed KA, Brown LV, von Gunten U. Essaïed KA, et al. Among authors: brown lv. Water Res. 2022 Feb 1;209:117864. doi: 10.1016/j.watres.2021.117864. Epub 2021 Nov 13. Water Res. 2022. PMID: 34847390 Free article.

4

Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients.

Kmieciak AE, Brown LV, Coles MC, Wagg J, Phipps A, Gaffney EA. Kmieciak AE, et al. Among authors: brown lv. Sci Rep. 2021 Aug 12;11(1):16394. doi: 10.1038/s41598-021-95225-x. Sci Rep. 2021. PMID: 34385480 Free PMC article.

5

Quantifying the limits of CAR T-cell delivery in mice and men.

Brown LV, Gaffney EA, Ager A, Wagg J, Coles MC. Brown LV, et al. J R Soc Interface. 2021 Mar;18(176):20201013. doi: 10.1098/rsif.2020.1013. Epub 2021 Mar 3. J R Soc Interface. 2021. PMID: 33653113 Free PMC article.

6

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease.

Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, Cragg S, Dehay B, Bitan G, Matute C, Bezard E, Wade-Martins R. Bengoa-Vergniory N, et al. Among authors: brown lv. Nat Commun. 2020 Sep 28;11(1):4885. doi: 10.1038/s41467-020-18689-x. Nat Commun. 2020. PMID: 32985503 Free PMC article.

7

Applications of mechanistic modelling to clinical and experimental immunology: an emerging technology to accelerate immunotherapeutic discovery and development.

Brown LV, Gaffney EA, Wagg J, Coles MC. Brown LV, et al. Clin Exp Immunol. 2018 Sep;193(3):284-292. doi: 10.1111/cei.13182. Clin Exp Immunol. 2018. PMID: 30240512 Free PMC article. Review.

8

An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination.

Brown LV, Gaffney EA, Wagg J, Coles MC. Brown LV, et al. J R Soc Interface. 2018 Mar;15(140):20180041. doi: 10.1098/rsif.2018.0041. J R Soc Interface. 2018. PMID: 29540543 Free PMC article.

9

Nanoscale Mapping and Spectroscopy of Nonradiative Hyperbolic Modes in Hexagonal Boron Nitride Nanostructures.

Brown LV, Davanco M, Sun Z, Kretinin A, Chen Y, Matson JR, Vurgaftman I, Sharac N, Giles AJ, Fogler MM, Taniguchi T, Watanabe K, Novoselov KS, Maier SA, Centrone A, Caldwell JD. Brown LV, et al. Nano Lett. 2018 Mar 14;18(3):1628-1636. doi: 10.1021/acs.nanolett.7b04476. Epub 2018 Feb 21. Nano Lett. 2018. PMID: 29451802 Free PMC article.

10

Help or Hindrance? The Support Person in the Psychiatric Medico-legal Examination.

Brown LV. Brown LV. Psychiatr Psychol Law. 2017 Nov 17;25(1):86-92. doi: 10.1080/13218719.2017.1351328. eCollection 2018. Psychiatr Psychol Law. 2017. PMID: 31984008 Free PMC article.

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