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Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production.
Reinert LS, Rashidi AS, Tran DN, Katzilieris-Petras G, Hvidt AK, Gohr M, Fruhwürth S, Bodda C, Thomsen MK, Vendelbo MH, Khan AR, Hansen B, Bergström P, Agholme L, Mogensen TH, Christensen MH, Nyengaard JR, Sen GC, Zetterberg H, Verjans GM, Paludan SR. Reinert LS, et al. Among authors: nyengaard jr. J Clin Invest. 2021 Jan 4;131(1):e136824. doi: 10.1172/JCI136824. J Clin Invest. 2021. PMID: 32990676 Free PMC article.
TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice.
Reinert LS, Harder L, Holm CK, Iversen MB, Horan KA, Dagnæs-Hansen F, Ulhøi BP, Holm TH, Mogensen TH, Owens T, Nyengaard JR, Thomsen AR, Paludan SR. Reinert LS, et al. Among authors: nyengaard jr. J Clin Invest. 2012 Apr;122(4):1368-76. doi: 10.1172/JCI60893. Epub 2012 Mar 19. J Clin Invest. 2012. PMID: 22426207 Free PMC article.
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.
Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, Nielsen R, Komatsu M, Nejsum LN, Jakobsen MR, Gyrd-Hansen M, Paludan SR. Prabakaran T, et al. Among authors: nyengaard jr. EMBO J. 2018 Apr 13;37(8):e97858. doi: 10.15252/embj.201797858. Epub 2018 Mar 1. EMBO J. 2018. PMID: 29496741 Free PMC article.
Fast diffusion kurtosis imaging of fibrotic mouse kidneys.
Kjølby BF, Khan AR, Chuhutin A, Pedersen L, Jensen JB, Jakobsen S, Zeidler D, Sangill R, Nyengaard JR, Jespersen SN, Hansen B. Kjølby BF, et al. Among authors: nyengaard jr. NMR Biomed. 2016 Dec;29(12):1709-1719. doi: 10.1002/nbm.3623. Epub 2016 Oct 12. NMR Biomed. 2016. PMID: 27731906 Free PMC article.
383 results