Ottmann OG - Search Results

1

A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia.

Lang F, Wunderle L, Badura S, Schleyer E, Brüggemann M, Serve H, Schnittger S, Gökbuget N, Pfeifer H, Wagner S, Ashelford K, Bug G, Ottmann OG. Lang F, et al. Among authors: ottmann og. BMC Pharmacol Toxicol. 2020 Sep 29;21(1):70. doi: 10.1186/s40360-020-00446-x. BMC Pharmacol Toxicol. 2020. PMID: 32993794 Free PMC article. Clinical Trial.

2

Characterization of defective megakaryocytic development in patients with myelodysplastic syndromes.

Hofmann WK, Kalina U, Wagner S, Seipelt G, Ries C, Hoelzer D, Ottmann OG. Hofmann WK, et al. Among authors: ottmann og. Exp Hematol. 1999 Mar;27(3):395-400. doi: 10.1016/s0301-472x(98)00077-0. Exp Hematol. 1999. PMID: 10089900 Free article.

3

IL-18 activates STAT3 in the natural killer cell line 92, augments cytotoxic activity, and mediates IFN-gamma production by the stress kinase p38 and by the extracellular regulated kinases p44erk-1 and p42erk-21.

Kalina U, Kauschat D, Koyama N, Nuernberger H, Ballas K, Koschmieder S, Bug G, Hofmann WK, Hoelzer D, Ottmann OG. Kalina U, et al. Among authors: ottmann og. J Immunol. 2000 Aug 1;165(3):1307-13. doi: 10.4049/jimmunol.165.3.1307. J Immunol. 2000. PMID: 10903731

4

Alteration of c-mpl-mediated signal transduction in CD34(+) cells from patients with myelodysplastic syndromes.

Kalina U, Hofmann WK, Koschmieder S, Wagner S, Kauschat D, Hoelzer D, Ottmann OG. Kalina U, et al. Among authors: ottmann og. Exp Hematol. 2000 Oct;28(10):1158-63. doi: 10.1016/s0301-472x(00)00527-0. Exp Hematol. 2000. PMID: 11027834 Free article.

5

Transforming growth factor-beta1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells.

Kalina U, Koschmieder S, Hofmann WK, Wagner S, Kauschat D, Hoelzer D, Ottmann OG. Kalina U, et al. Among authors: ottmann og. Exp Hematol. 2001 May;29(5):602-8. doi: 10.1016/s0301-472x(01)00628-2. Exp Hematol. 2001. PMID: 11376873 Free article.

6

TGF beta-induced SMAD2 phosphorylation predicts inhibition of thymidine incorporation in CD34+ cells from healthy donors, but not from patients with AML after MDS.

Koschmieder S, Hofmann WK, Kunert J, Wagner S, Ballas K, Seipelt G, Hoelzer D, Ottmann OG, Kalina U. Koschmieder S, et al. Among authors: ottmann og. Leukemia. 2001 Jun;15(6):942-9. doi: 10.1038/sj.leu.2402119. Leukemia. 2001. PMID: 11417481

7

Interleukin 3 improves the ex vivo expansion of primitive human cord blood progenitor cells and maintains the engraftment potential of scid repopulating cells.

Rossmanith T, Schröder B, Bug G, Müller P, Klenner T, Knaus R, Hoelzer D, Ottmann OG. Rossmanith T, et al. Among authors: ottmann og. Stem Cells. 2001;19(4):313-20. doi: 10.1634/stemcells.19-4-313. Stem Cells. 2001. PMID: 11463951

8

Hematologic and cytogenetic remission by STI571 (Glivec) in a patient relapsing with accelerated phase CML after second allogeneic stem cell transplantation.

Wassmann B, Klein SA, Scheuring U, Pfeifer H, Martin H, Gschaidmeier H, Hoelzer D, Ottmann OG. Wassmann B, et al. Among authors: ottmann og. Bone Marrow Transplant. 2001 Oct;28(7):721-4. doi: 10.1038/sj.bmt.1703222. Bone Marrow Transplant. 2001. PMID: 11704799

9

Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells.

Bug G, Rossmanith T, Henschler R, Kunz-Schughart LA, Schröder B, Kampfmann M, Kreutz M, Hoelzer D, Ottmann OG. Bug G, et al. Among authors: ottmann og. J Leukoc Biol. 2002 Oct;72(4):837-45. J Leukoc Biol. 2002. PMID: 12377954

10

Early minimal residual disease (MRD) analysis during treatment of Philadelphia chromosome/Bcr-Abl-positive acute lymphoblastic leukemia with the Abl-tyrosine kinase inhibitor imatinib (STI571).

Scheuring UJ, Pfeifer H, Wassmann B, Bruck P, Atta J, Petershofen EK, Gehrke B, Gschaidmeier H, Hoelzer D, Ottmann OG. Scheuring UJ, et al. Among authors: ottmann og. Blood. 2003 Jan 1;101(1):85-90. doi: 10.1182/blood-2002-02-0360. Epub 2002 Aug 22. Blood. 2003. PMID: 12393581 Free article. Clinical Trial.

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