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Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors.
Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, Cirolia G, Thomas D, Stamnes S, Holt K, Sinn P, May AP, Paulk NK. Rumachik NG, et al. Among authors: cirolia g. Mol Ther Methods Clin Dev. 2020 May 22;18:98-118. doi: 10.1016/j.omtm.2020.05.018. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32995354 Free PMC article.
Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. Leenay RT, et al. Among authors: cirolia g. Nat Biotechnol. 2019 Sep;37(9):1034-1037. doi: 10.1038/s41587-019-0203-2. Epub 2019 Jul 29. Nat Biotechnol. 2019. PMID: 31359007 Free PMC article.
CRISPR-based functional genomics in human dendritic cells.
Jost M, Jacobson AN, Hussmann JA, Cirolia G, Fischbach MA, Weissman JS. Jost M, et al. Among authors: cirolia g. Elife. 2021 Apr 27;10:e65856. doi: 10.7554/eLife.65856. Elife. 2021. PMID: 33904395 Free PMC article.
Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris.
Tabula Muris Consortium; Overall coordination; Logistical coordination; Organ collection and processing; Library preparation and sequencing; Computational data analysis; Cell type annotation; Writing group; Supplemental text writing group; Principal investigators. Tabula Muris Consortium, et al. Nature. 2018 Oct;562(7727):367-372. doi: 10.1038/s41586-018-0590-4. Epub 2018 Oct 3. Nature. 2018. PMID: 30283141 Free PMC article.