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Page 1
Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Hoang TN, Pino M, Boddapati AK, Viox EG, Starke CE, Upadhyay AA, Gumber S, Busman-Sahay K, Strongin Z, Harper JL, Tharp GK, Pellegrini KL, Kirejczyk S, Zandi K, Tao S, Horton TR, Beagle EN, Mahar EA, Lee MY, Cohen J, Jean SM, Wood JS, Connor-Stroud F, Stammen RL, Delmas OM, Wang S, Cooney KA, Sayegh MN, Wang L, Weiskopf D, Filev PD, Waggoner J, Piantadosi A, Kasturi SP, Al-Shakhshir H, Ribeiro SP, Sekaly RP, Levit RD, Estes JD, Vanderford TH, Schinazi RF, Bosinger SE, Paiardini M. Hoang TN, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2020 Sep 16:2020.09.16.300277. doi: 10.1101/2020.09.16.300277. bioRxiv. 2020. Update in: Cell. 2021 Jan 21;184(2):460-475.e21. doi: 10.1016/j.cell.2020.11.007 PMID: 32995780 Free PMC article. Updated. Preprint.
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Hoang TN, Pino M, Boddapati AK, Viox EG, Starke CE, Upadhyay AA, Gumber S, Nekorchuk M, Busman-Sahay K, Strongin Z, Harper JL, Tharp GK, Pellegrini KL, Kirejczyk S, Zandi K, Tao S, Horton TR, Beagle EN, Mahar EA, Lee MYH, Cohen J, Jean SM, Wood JS, Connor-Stroud F, Stammen RL, Delmas OM, Wang S, Cooney KA, Sayegh MN, Wang L, Filev PD, Weiskopf D, Silvestri G, Waggoner J, Piantadosi A, Kasturi SP, Al-Shakhshir H, Ribeiro SP, Sekaly RP, Levit RD, Estes JD, Vanderford TH, Schinazi RF, Bosinger SE, Paiardini M. Hoang TN, et al. Among authors: weiskopf d. Cell. 2021 Jan 21;184(2):460-475.e21. doi: 10.1016/j.cell.2020.11.007. Epub 2020 Nov 10. Cell. 2021. PMID: 33278358 Free PMC article.
Immunological memory to SARS-CoV-2 assessed for up to eight months after infection.
Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. Dan JM, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2020 Dec 18:2020.11.15.383323. doi: 10.1101/2020.11.15.383323. bioRxiv. 2020. Update in: Science. 2021 Feb 5;371(6529):eabf4063. doi: 10.1126/science.abf4063 PMID: 33442687 Free PMC article. Updated. Preprint.
A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
Pino M, Abid T, Pereira Ribeiro S, Edara VV, Floyd K, Smith JC, Latif MB, Pacheco-Sanchez G, Dutta D, Wang S, Gumber S, Kirejczyk S, Cohen J, Stammen RL, Jean SM, Wood JS, Connor-Stroud F, Pollet J, Chen WH, Wei J, Zhan B, Lee J, Liu Z, Strych U, Shenvi N, Easley K, Weiskopf D, Sette A, Pollara J, Mielke D, Gao H, Eisel N, LaBranche CC, Shen X, Ferrari G, Tomaras GD, Montefiori DC, Sekaly RP, Vanderford TH, Tomai MA, Fox CB, Suthar MS, Kozlowski PA, Hotez PJ, Paiardini M, Bottazzi ME, Kasturi SP. Pino M, et al. Among authors: weiskopf d. Sci Immunol. 2021 Jul 15;6(61):eabh3634. doi: 10.1126/sciimmunol.abh3634. Sci Immunol. 2021. PMID: 34266981 Free PMC article.
mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern.
Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit; Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: weiskopf d, d andrea k. bioRxiv [Preprint]. 2021 Aug 23:2021.08.23.457229. doi: 10.1101/2021.08.23.457229. bioRxiv. 2021. Update in: Science. 2021 Dec 03;374(6572):abm0829. doi: 10.1126/science.abm0829 PMID: 34462751 Free PMC article. Updated. Preprint.
Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period.
Yu ED, Narowski TM, Wang E, Garrigan E, Mateus J, Frazier A, Weiskopf D, Grifoni A, Premkumar L, da Silva Antunes R, Sette A. Yu ED, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2022 Mar 2:2022.03.01.482548. doi: 10.1101/2022.03.01.482548. bioRxiv. 2022. Update in: Cell Host Microbe. 2022 Sep 14;30(9):1269-1278.e4. doi: 10.1016/j.chom.2022.07.012 PMID: 35262082 Free PMC article. Updated. Preprint.
SARS-CoV-2 Evolution and Immune Escape in Immunocompromised Patients.
Scherer EM, Babiker A, Adelman MW, Allman B, Key A, Kleinhenz JM, Langsjoen RM, Nguyen PV, Onyechi I, Sherman JD, Simon TW, Soloff H, Tarabay J, Varkey J, Webster AS, Weiskopf D, Weissman DB, Xu Y, Waggoner JJ, Koelle K, Rouphael N, Pouch SM, Piantadosi A. Scherer EM, et al. Among authors: weiskopf d. N Engl J Med. 2022 Jun 23;386(25):2436-2438. doi: 10.1056/NEJMc2202861. Epub 2022 Jun 8. N Engl J Med. 2022. PMID: 35675197 Free PMC article. No abstract available.
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Nelson CE, Foreman TW, Kauffman KD, Sakai S, Gould ST, Fleegle JD, Gomez F; NIAID/DIR Tuberculosis Imaging Program; Le Nouën C, Liu X, Burdette TL, Garza NL, Lafont BAP, Brooks K, Arlehamn CSL, Weiskopf D, Sette A, Hickman HD, Buchholz UJ, Johnson RF, Brenchley JM, Via LE, Barber DL. Nelson CE, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2022 Sep 15:2022.09.13.507852. doi: 10.1101/2022.09.13.507852. bioRxiv. 2022. Update in: PLoS Pathog. 2024 Jul 1;20(7):e1012339. doi: 10.1371/journal.ppat.1012339 PMID: 36172119 Free PMC article. Updated. Preprint.
Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses.
Tarke A, Zhang Y, Methot N, Narowski TM, Phillips E, Mallal S, Frazier A, Filaci G, Weiskopf D, Dan JM, Premkumar L, Scheuermann RH, Sette A, Grifoni A. Tarke A, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2023 Jan 5:2023.01.04.522794. doi: 10.1101/2023.01.04.522794. bioRxiv. 2023. Update in: Cell Rep Med. 2023 Jun 20;4(6):101088. doi: 10.1016/j.xcrm.2023.101088 PMID: 36656777 Free PMC article. Updated. Preprint.
Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies.
Painter MM, Johnston TS, Lundgreen KA, Santos JJS, Qin JS, Goel RR, Apostolidis SA, Mathew D, Fulmer B, Williams JC, McKeague ML, Pattekar A, Goode A, Nasta S, Baxter AE, Giles JR, Skelly AN, Felley LE, McLaughlin M, Weaver J; Penn Medicine BioBank; Kuthuru O, Dougherty J, Adamski S, Long S, Kee M, Clendenin C, da Silva Antunes R, Grifoni A, Weiskopf D, Sette A, Huang AC, Rader DJ, Hensley SE, Bates P, Greenplate AR, Wherry EJ. Painter MM, et al. Among authors: weiskopf d. bioRxiv [Preprint]. 2023 Feb 6:2023.02.05.527215. doi: 10.1101/2023.02.05.527215. bioRxiv. 2023. Update in: Nat Immunol. 2023 Oct;24(10):1711-1724. doi: 10.1038/s41590-023-01613-y PMID: 36798171 Free PMC article. Updated. Preprint.
295 results