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LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.
Chen Y, Jiang T, Zhang H, Gou X, Han C, Wang J, Chen AT, Ma J, Liu J, Chen Z, Jing X, Lei H, Wang Z, Bao Y, Baqri M, Zhu Y, Bindra RS, Hansen JE, Dou J, Huang C, Zhou J. Chen Y, et al. Among authors: bindra rs. Nat Cell Biol. 2020 Oct;22(10):1276-1285. doi: 10.1038/s41556-020-00586-6. Epub 2020 Oct 1. Nat Cell Biol. 2020. PMID: 33005030 Free PMC article.
Temozolomide Sensitizes MGMT-Deficient Tumor Cells to ATR Inhibitors.
Jackson CB, Noorbakhsh SI, Sundaram RK, Kalathil AN, Ganesa S, Jia L, Breslin H, Burgenske DM, Gilad O, Sarkaria JN, Bindra RS. Jackson CB, et al. Among authors: bindra rs. Cancer Res. 2019 Sep 1;79(17):4331-4338. doi: 10.1158/0008-5472.CAN-18-3394. Epub 2019 Jul 4. Cancer Res. 2019. PMID: 31273061 Free PMC article.
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Sulkowski PL, Oeck S, Dow J, Economos NG, Mirfakhraie L, Liu Y, Noronha K, Bao X, Li J, Shuch BM, King MC, Bindra RS, Glazer PM. Sulkowski PL, et al. Among authors: bindra rs. Nature. 2020 Jun;582(7813):586-591. doi: 10.1038/s41586-020-2363-0. Epub 2020 Jun 3. Nature. 2020. PMID: 32494005 Free PMC article.
Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance.
Wang Y, Jiang Y, Wei D, Singh P, Yu Y, Lee T, Zhang L, Mandl HK, Piotrowski-Daspit AS, Chen X, Li F, Li X, Cheng Y, Josowitz A, Yang F, Zhao Y, Wang F, Zhao Z, Huttner A, Bindra RS, Xiao H, Mark Saltzman W. Wang Y, et al. Among authors: bindra rs. Nat Biomed Eng. 2021 Sep;5(9):1048-1058. doi: 10.1038/s41551-021-00728-7. Epub 2021 May 27. Nat Biomed Eng. 2021. PMID: 34045730 Free PMC article.
Regulation of DNA repair in hypoxic cancer cells.
Bindra RS, Crosby ME, Glazer PM. Bindra RS, et al. Cancer Metastasis Rev. 2007 Jun;26(2):249-60. doi: 10.1007/s10555-007-9061-3. Cancer Metastasis Rev. 2007. PMID: 17415527 Review.
116 results