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Page 1
Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition.
Kakiyama G, Marques D, Martin R, Takei H, Rodriguez-Agudo D, LaSalle SA, Hashiguchi T, Liu X, Green R, Erickson S, Gil G, Fuchs M, Suzuki M, Murai T, Nittono H, Hylemon PB, Zhou H, Pandak WM. Kakiyama G, et al. J Lipid Res. 2020 Dec;61(12):1629-1644. doi: 10.1194/jlr.RA120000924. Epub 2020 Oct 2. J Lipid Res. 2020. PMID: 33008924 Free PMC article.
Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.
Bai Q, Zhang X, Xu L, Kakiyama G, Heuman D, Sanyal A, Pandak WM, Yin L, Xie W, Ren S. Bai Q, et al. Among authors: kakiyama g. Metabolism. 2012 Jun;61(6):836-45. doi: 10.1016/j.metabol.2011.11.014. Epub 2012 Jan 5. Metabolism. 2012. PMID: 22225954 Free PMC article.
Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.
Kakiyama G, Pandak WM, Gillevet PM, Hylemon PB, Heuman DM, Daita K, Takei H, Muto A, Nittono H, Ridlon JM, White MB, Noble NA, Monteith P, Fuchs M, Thacker LR, Sikaroodi M, Bajaj JS. Kakiyama G, et al. J Hepatol. 2013 May;58(5):949-55. doi: 10.1016/j.jhep.2013.01.003. Epub 2013 Jan 16. J Hepatol. 2013. PMID: 23333527 Free PMC article.
Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis.
Bajaj JS, Heuman DM, Hylemon PB, Sanyal AJ, Puri P, Sterling RK, Luketic V, Stravitz RT, Siddiqui MS, Fuchs M, Thacker LR, Wade JB, Daita K, Sistrun S, White MB, Noble NA, Thorpe C, Kakiyama G, Pandak WM, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: kakiyama g. Aliment Pharmacol Ther. 2014 May;39(10):1113-25. doi: 10.1111/apt.12695. Epub 2014 Mar 16. Aliment Pharmacol Ther. 2014. PMID: 24628464 Free PMC article. Clinical Trial.
59 results