Wagstaff J - Search Results

1

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.

Douse CH, Tchasovnikarova IA, Timms RT, Protasio AV, Seczynska M, Prigozhin DM, Albecka A, Wagstaff J, Williamson JC, Freund SMV, Lehner PJ, Modis Y. Douse CH, et al. Among authors: wagstaff j. Nat Commun. 2020 Oct 2;11(1):4940. doi: 10.1038/s41467-020-18761-6. Nat Commun. 2020. PMID: 33009411 Free PMC article.

2

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.

Wauer T, Swatek KN, Wagstaff JL, Gladkova C, Pruneda JN, Michel MA, Gersch M, Johnson CM, Freund SM, Komander D. Wauer T, et al. EMBO J. 2015 Feb 3;34(3):307-25. doi: 10.15252/embj.201489847. Epub 2014 Dec 19. EMBO J. 2015. PMID: 25527291 Free PMC article.

3

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D. Michel MA, et al. Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5. Mol Cell. 2015. PMID: 25752577 Free PMC article.

4

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M. Elliott PR, et al. Among authors: wagstaff j. Mol Cell. 2016 Sep 15;63(6):990-1005. doi: 10.1016/j.molcel.2016.08.001. Epub 2016 Aug 30. Mol Cell. 2016. PMID: 27591049 Free PMC article.

5

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C.

Ho AK, Wagstaff JL, Manna PT, Wartosch L, Qamar S, Garman EF, Freund SM, Roberts RC. Ho AK, et al. BMC Biol. 2016 Dec 7;14(1):109. doi: 10.1186/s12915-016-0332-8. BMC Biol. 2016. PMID: 27927196 Free PMC article.

6

An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.

Gladkova C, Schubert AF, Wagstaff JL, Pruneda JN, Freund SM, Komander D. Gladkova C, et al. EMBO J. 2017 Dec 15;36(24):3555-3572. doi: 10.15252/embj.201797876. Epub 2017 Nov 13. EMBO J. 2017. PMID: 29133469 Free PMC article.

7

Structure of PINK1 in complex with its substrate ubiquitin.

Schubert AF, Gladkova C, Pardon E, Wagstaff JL, Freund SMV, Steyaert J, Maslen SL, Komander D. Schubert AF, et al. Among authors: wagstaff jl. Nature. 2017 Dec 7;552(7683):51-56. doi: 10.1038/nature24645. Epub 2017 Oct 30. Nature. 2017. PMID: 29160309 Free PMC article.

8

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.

Stowell JAW, Wagstaff JL, Hill CH, Yu M, McLaughlin SH, Freund SMV, Passmore LA. Stowell JAW, et al. J Biol Chem. 2018 Jun 15;293(24):9210-9222. doi: 10.1074/jbc.RA118.002291. Epub 2018 Apr 25. J Biol Chem. 2018. PMID: 29695507 Free PMC article.

9

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.

Gersch M, Wagstaff JL, Toms AV, Graves B, Freund SMV, Komander D. Gersch M, et al. Mol Cell. 2019 May 2;74(3):436-451.e7. doi: 10.1016/j.molcel.2019.02.030. Epub 2019 Mar 26. Mol Cell. 2019. PMID: 30926242 Free PMC article.

10

Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.

Heimhalt M, Berndt A, Wagstaff J, Anandapadamanaban M, Perisic O, Maslen S, McLaughlin S, Yu CW, Masson GR, Boland A, Ni X, Yamashita K, Murshudov GN, Skehel M, Freund SM, Williams RL. Heimhalt M, et al. Among authors: wagstaff j. Elife. 2021 Sep 14;10:e68799. doi: 10.7554/eLife.68799. Elife. 2021. PMID: 34519269 Free PMC article.

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