Jeggo P - Search Results

1

Haematopoietic Stem Cell Transplantation for DNA Ligase 1 Deficiency.

Silva JMF, Jones A, Sibson K, Bibi S, Jeggo P, Woodbine L, Ahsan G, Gilmour KC, Rao K, Chiesa R, Lucchini G, Veys P, Worth A, Amrolia PJ. Silva JMF, et al. Among authors: jeggo p. J Clin Immunol. 2021 Jan;41(1):238-242. doi: 10.1007/s10875-020-00871-x. Epub 2020 Oct 6. J Clin Immunol. 2021. PMID: 33025376 No abstract available.

2

Nbs1 is required for ATR-dependent phosphorylation events.

Stiff T, Reis C, Alderton GK, Woodbine L, O'Driscoll M, Jeggo PA. Stiff T, et al. EMBO J. 2005 Jan 12;24(1):199-208. doi: 10.1038/sj.emboj.7600504. Epub 2004 Dec 16. EMBO J. 2005. PMID: 15616588 Free PMC article.

3

Radiation-induced delayed cell death in a hypomorphic Artemis cell line.

Evans PM, Woodbine L, Riballo E, Gennery AR, Hubank M, Jeggo PA. Evans PM, et al. Hum Mol Genet. 2006 Apr 15;15(8):1303-11. doi: 10.1093/hmg/ddl050. Epub 2006 Mar 15. Hum Mol Genet. 2006. PMID: 16540517

4

Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK.

Costantini S, Woodbine L, Andreoli L, Jeggo PA, Vindigni A. Costantini S, et al. DNA Repair (Amst). 2007 Jun 1;6(6):712-22. doi: 10.1016/j.dnarep.2006.12.007. Epub 2007 Jan 22. DNA Repair (Amst). 2007. PMID: 17241822

5

DNA repair is limiting for haematopoietic stem cells during ageing.

Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ. Nijnik A, et al. Among authors: jeggo pa. Nature. 2007 Jun 7;447(7145):686-90. doi: 10.1038/nature05875. Nature. 2007. PMID: 17554302

6

XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation.

Riballo E, Woodbine L, Stiff T, Walker SA, Goodarzi AA, Jeggo PA. Riballo E, et al. Nucleic Acids Res. 2009 Feb;37(2):482-92. doi: 10.1093/nar/gkn957. Epub 2008 Dec 4. Nucleic Acids Res. 2009. PMID: 19056826 Free PMC article.

7

Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.

Nijnik A, Dawson S, Crockford TL, Woodbine L, Visetnoi S, Bennett S, Jones M, Turner GD, Jeggo PA, Goodnow CC, Cornall RJ. Nijnik A, et al. J Clin Invest. 2009 Jun;119(6):1696-705. doi: 10.1172/JCI32743. Epub 2009 May 18. J Clin Invest. 2009. PMID: 19451691 Free PMC article.

8

Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

Löser DA, Shibata A, Shibata AK, Woodbine LJ, Jeggo PA, Chalmers AJ. Löser DA, et al. Mol Cancer Ther. 2010 Jun;9(6):1775-87. doi: 10.1158/1535-7163.MCT-09-1027. Epub 2010 Jun 8. Mol Cancer Ther. 2010. PMID: 20530711 Free PMC article.

9

An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity.

Woodbine L, Grigoriadou S, Goodarzi AA, Riballo E, Tape C, Oliver AW, van Zelm MC, Buckland MS, Davies EG, Pearl LH, Jeggo PA. Woodbine L, et al. DNA Repair (Amst). 2010 Sep 4;9(9):1003-10. doi: 10.1016/j.dnarep.2010.07.001. Epub 2010 Jul 31. DNA Repair (Amst). 2010. PMID: 20674517

10

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair.

Woodbine L, Brunton H, Goodarzi AA, Shibata A, Jeggo PA. Woodbine L, et al. Among authors: jeggo pa. Nucleic Acids Res. 2011 Sep 1;39(16):6986-97. doi: 10.1093/nar/gkr331. Epub 2011 May 19. Nucleic Acids Res. 2011. PMID: 21596788 Free PMC article.

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