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Page 1
Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
Fujikura K, Hosoda W, Felsenstein M, Song Q, Reiter JG, Zheng L, Beleva Guthrie V, Rincon N, Dal Molin M, Dudley J, Cohen JD, Wang P, Fischer CG, Braxton AM, Noë M, Jongepier M, Fernández-Del Castillo C, Mino-Kenudson M, Schmidt CM, Yip-Schneider MT, Lawlor RT, Salvia R, Roberts NJ, Thompson ED, Karchin R, Lennon AM, Jiao Y, Wood LD. Fujikura K, et al. Among authors: roberts nj. Gut. 2021 May;70(5):928-939. doi: 10.1136/gutjnl-2020-321217. Epub 2020 Oct 7. Gut. 2021. PMID: 33028669 Free PMC article.
ATM mutations in patients with hereditary pancreatic cancer.
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu VE, Goggins M, Vogelstein B, Papadopoulos N, Hruban RH, Kinzler KW, Klein AP. Roberts NJ, et al. Cancer Discov. 2012 Jan;2(1):41-6. doi: 10.1158/2159-8290.CD-11-0194. Epub 2011 Dec 29. Cancer Discov. 2012. PMID: 22585167 Free PMC article.
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.
Agrawal N, Jiao Y, Sausen M, Leary R, Bettegowda C, Roberts NJ, Bhan S, Ho AS, Khan Z, Bishop J, Westra WH, Wood LD, Hruban RH, Tufano RP, Robinson B, Dralle H, Toledo SP, Toledo RA, Morris LG, Ghossein RA, Fagin JA, Chan TA, Velculescu VE, Vogelstein B, Kinzler KW, Papadopoulos N, Nelkin BD, Ball DW. Agrawal N, et al. Among authors: roberts nj. J Clin Endocrinol Metab. 2013 Feb;98(2):E364-9. doi: 10.1210/jc.2012-2703. Epub 2012 Dec 21. J Clin Endocrinol Metab. 2013. PMID: 23264394 Free PMC article.
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.
Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP. Roberts NJ, et al. Cancer Discov. 2016 Feb;6(2):166-75. doi: 10.1158/2159-8290.CD-15-0402. Epub 2015 Dec 9. Cancer Discov. 2016. PMID: 26658419 Free PMC article.
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, Papadopoulos N. Robles AI, et al. Among authors: roberts nj. Gastroenterology. 2016 Apr;150(4):931-43. doi: 10.1053/j.gastro.2015.12.036. Epub 2016 Jan 5. Gastroenterology. 2016. PMID: 26764183 Free PMC article.
Exome-Wide Association Study of Pancreatic Cancer Risk.
Grant RC, Denroche RE, Borgida A, Virtanen C, Cook N, Smith AL, Connor AA, Wilson JM, Peterson G, Roberts NJ, Klein AP, Grimmond SM, Biankin A, Cleary S, Moore M, Lemire M, Zogopoulos G, Stein L, Gallinger S. Grant RC, et al. Among authors: roberts nj. Gastroenterology. 2018 Feb;154(3):719-722.e3. doi: 10.1053/j.gastro.2017.10.015. Epub 2017 Oct 24. Gastroenterology. 2018. PMID: 29074453 Free PMC article.
IPMNs with co-occurring invasive cancers: neighbours but not always relatives.
Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD. Felsenstein M, et al. Among authors: roberts nj. Gut. 2018 Sep;67(9):1652-1662. doi: 10.1136/gutjnl-2017-315062. Epub 2018 Mar 2. Gut. 2018. PMID: 29500184 Free PMC article.
Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology.
Noë M, Rezaee N, Asrani K, Skaro M, Groot VP, Wu PH, Olson MT, Hong SM, Kim SJ, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wirtz D, Roberts NJ, Offerhaus GJA, Brosens LAA, Wood LD, Hruban RH. Noë M, et al. Among authors: roberts nj. Am J Pathol. 2018 Jul;188(7):1530-1535. doi: 10.1016/j.ajpath.2018.04.002. Epub 2018 Apr 22. Am J Pathol. 2018. PMID: 29684363 Free PMC article.
Whole-exome sequencing of duodenal neuroendocrine tumors in patients with neurofibromatosis type 1.
Noë M, Pea A, Luchini C, Felsenstein M, Barbi S, Bhaijee F, Yonescu R, Ning Y, Adsay NV, Zamboni G, Lawlor RT, Scarpa A, Offerhaus GJA, Brosens LAA, Hruban RH, Roberts NJ, Wood LD. Noë M, et al. Among authors: roberts nj. Mod Pathol. 2018 Oct;31(10):1532-1538. doi: 10.1038/s41379-018-0082-y. Epub 2018 May 30. Mod Pathol. 2018. PMID: 29849115 Free PMC article.
Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.
Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD. Kuboki Y, et al. Among authors: roberts nj. J Pathol. 2019 Mar;247(3):347-356. doi: 10.1002/path.5194. Epub 2019 Jan 16. J Pathol. 2019. PMID: 30430578 Free PMC article.
281 results