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Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Among authors: ley am. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting.
Joyner CJ, Ley AM, Nguyen DC, Ali M, Corrado A, Tipton C, Scharer CD, Mi T, Woodruff MC, Hom J, Boss JM, Duan M, Gibson G, Roberts D, Andrews J, Lonial S, Sanz I, Lee FE. Joyner CJ, et al. Among authors: ley am. Life Sci Alliance. 2021 Dec 24;5(3):e202101285. doi: 10.26508/lsa.202101285. Print 2022 Mar. Life Sci Alliance. 2021. PMID: 34952892 Free PMC article.
Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.
Woodruff M, Ramonell R, Cashman K, Nguyen D, Saini A, Haddad N, Ley A, Kyu S, Howell JC, Ozturk T, Lee S, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam F, Sharma M, Wu H, Le S, Jenks S, Tipton CM, Hu W, Lee FE, Sanz I. Woodruff M, et al. medRxiv [Preprint]. 2020 Jun 22:2020.04.29.20083717. doi: 10.1101/2020.04.29.20083717. medRxiv. 2020. Update in: Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z PMID: 32511635 Free PMC article. Updated. Preprint.
Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.
Sissung TM, Huang PA, Hauke RJ, McCrea EM, Peer CJ, Barbier RH, Strope JD, Ley AM, Zhang M, Hong JA, Venzon D, Jackson JP, Brouwer KR, Grohar P, Glod J, Widemann BC, Heller T, Schrump DS, Figg WD. Sissung TM, et al. Among authors: ley am. Mol Pharmacol. 2019 Aug;96(2):158-167. doi: 10.1124/mol.118.114827. Epub 2019 Jun 7. Mol Pharmacol. 2019. PMID: 31175181 Free PMC article.
Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.
Sissung TM, Ley AM, Strope JD, McCrea EM, Beedie S, Peer CJ, Shukla S, van Velkinburgh J, Reece K, Troutman S, Campbell T, Fernandez E, Huang P, Smith J, Thakkar N, Venzon DJ, Brenner S, Lee W, Merino M, Luo J, Jager W, Price DK, Chau CH, Figg WD. Sissung TM, et al. Among authors: ley am. Mol Cancer Res. 2017 Aug;15(8):1096-1105. doi: 10.1158/1541-7786.MCR-16-0477. Epub 2017 Apr 7. Mol Cancer Res. 2017. PMID: 28389619 Free PMC article.
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