Zhu L - Search Results

1

Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.

Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Among authors: zhu l. Protein Cell. 2021 Jan;12(1):76-80. doi: 10.1007/s13238-020-00792-w. Protein Cell. 2021. PMID: 33029721 Free PMC article. No abstract available.

2

Discovery of non-peptide inhibitors of Plasmepsin II by structure-based virtual screening.

Song Y, Jin H, Liu X, Zhu L, Huang J, Li H. Song Y, et al. Among authors: zhu l. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2078-82. doi: 10.1016/j.bmcl.2013.01.128. Epub 2013 Feb 9. Bioorg Med Chem Lett. 2013. PMID: 23466235

3

Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening.

Wang L, Yang C, Lu W, Liu L, Gao R, Liao S, Zhao Z, Zhu L, Xu Y, Li H, Huang J, Zhu W. Wang L, et al. Among authors: zhu w, zhu l. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3496-9. doi: 10.1016/j.bmcl.2013.04.048. Epub 2013 Apr 29. Bioorg Med Chem Lett. 2013. PMID: 23664215

4

Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives.

Xu M, Zhu J, Diao Y, Zhou H, Ren X, Sun D, Huang J, Han D, Zhao Z, Zhu L, Xu Y, Li H. Xu M, et al. Among authors: zhu j, zhu l. J Med Chem. 2013 Oct 24;56(20):7911-24. doi: 10.1021/jm400938g. Epub 2013 Oct 11. J Med Chem. 2013. PMID: 24073986

5

Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening.

Wang L, Zhang S, Zhu J, Zhu L, Liu X, Shan L, Huang J, Zhang W, Li H. Wang L, et al. Among authors: zhu j, zhu l. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1261-4. doi: 10.1016/j.bmcl.2014.01.074. Epub 2014 Feb 2. Bioorg Med Chem Lett. 2014. PMID: 24530004

6

Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase.

Zhu J, Han L, Diao Y, Ren X, Xu M, Xu L, Li S, Li Q, Dong D, Huang J, Liu X, Zhao Z, Wang R, Zhu L, Xu Y, Qian X, Li H. Zhu J, et al. Among authors: zhu l. J Med Chem. 2015 Feb 12;58(3):1123-39. doi: 10.1021/jm501127s. Epub 2015 Jan 26. J Med Chem. 2015. PMID: 25580811

7

Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity.

Li S, Luan G, Ren X, Song W, Xu L, Xu M, Zhu J, Dong D, Diao Y, Liu X, Zhu L, Wang R, Zhao Z, Xu Y, Li H. Li S, et al. Among authors: zhu j, zhu l. Sci Rep. 2015 Oct 7;5:14836. doi: 10.1038/srep14836. Sci Rep. 2015. PMID: 26443076 Free PMC article.

8

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes.

Li S, Xu H, Cui S, Wu F, Zhang Y, Su M, Gong Y, Qiu S, Jiao Q, Qin C, Shan J, Zhang M, Wang J, Yin Q, Xu M, Liu X, Wang R, Zhu L, Li J, Xu Y, Jiang H, Zhao Z, Li J, Li H. Li S, et al. Among authors: zhu l. J Med Chem. 2016 Jul 28;59(14):6772-90. doi: 10.1021/acs.jmedchem.6b00505. Epub 2016 Jul 19. J Med Chem. 2016. PMID: 27396490

9

Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation.

Hao Y, Wang X, Zhang T, Sun D, Tong Y, Xu Y, Chen H, Tong L, Zhu L, Zhao Z, Chen Z, Ding J, Xie H, Xu Y, Li H. Hao Y, et al. Among authors: zhu l. J Med Chem. 2016 Aug 11;59(15):7111-24. doi: 10.1021/acs.jmedchem.6b00403. Epub 2016 Jul 21. J Med Chem. 2016. PMID: 27396610

10

Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor.

Li Q, Quan L, Lyu J, He Z, Wang X, Meng J, Zhao Z, Zhu L, Liu X, Li H. Li Q, et al. Among authors: zhu l. Oncotarget. 2016 Oct 4;7(40):64967-64976. doi: 10.18632/oncotarget.11274. Oncotarget. 2016. PMID: 27533458 Free PMC article.

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