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JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency.
Huang Y, Zhang H, Wang L, Tang C, Qin X, Wu X, Pan M, Tang Y, Yang Z, Babarinde IA, Lin R, Ji G, Lai Y, Xu X, Su J, Wen X, Satoh T, Ahmed T, Malik V, Ward C, Volpe G, Guo L, Chen J, Sun L, Li Y, Huang X, Bao X, Gao F, Liu B, Zheng H, Jauch R, Lai L, Pan G, Chen J, Testa G, Akira S, Hu J, Pei D, Hutchins AP, Esteban MA, Qin B. Huang Y, et al. Among authors: huang x. Nat Commun. 2020 Oct 8;11(1):5061. doi: 10.1038/s41467-020-18900-z. Nat Commun. 2020. PMID: 33033262 Free PMC article.
Gadd45a is a heterochromatin relaxer that enhances iPS cell generation.
Chen K, Long Q, Wang T, Zhao D, Zhou Y, Qi J, Wu Y, Li S, Chen C, Zeng X, Yang J, Zhou Z, Qin W, Liu X, Li Y, Li Y, Huang X, Qin D, Chen J, Pan G, Schöler HR, Xu G, Liu X, Pei D. Chen K, et al. Among authors: huang x. EMBO Rep. 2016 Nov;17(11):1641-1656. doi: 10.15252/embr.201642402. Epub 2016 Oct 4. EMBO Rep. 2016. PMID: 27702986 Free PMC article.
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