Mettu VS - Search Results

1

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs.

Ranjit A, Lee CB, Tenora L, Mettu VS, Pal A, Alt J, Slusher BS, Rais R. Ranjit A, et al. Among authors: mettu vs. Pharmaceutics. 2024 Dec 26;17(1):20. doi: 10.3390/pharmaceutics17010020. Pharmaceutics. 2024. PMID: 39861669

2

Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans?

Thakur A, Yue G, Ahire D, Mettu VS, Al Maghribi A, Ford K, Peixoto L, Leeder JS, Prasad B. Thakur A, et al. Among authors: mettu vs. Clin Pharmacol Ther. 2024 Jul;116(1):235-246. doi: 10.1002/cpt.3277. Epub 2024 May 6. Clin Pharmacol Ther. 2024. PMID: 38711199

3

Effect of Cimetidine on Metformin Pharmacokinetics and Endogenous Metabolite Levels in Rats.

Ailabouni AS, Mettu VS, Thakur A, Singh DK, Prasad B. Ailabouni AS, et al. Among authors: mettu vs. Drug Metab Dispos. 2024 Jan 9;52(2):86-94. doi: 10.1124/dmd.123.001470. Drug Metab Dispos. 2024. PMID: 38049999

4

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.

Novotná K, Tenora L, Prchalová E, Paule J, Alt J, Veeravalli V, Lam J, Wu Y, Šnajdr I, Gori S, Mettu VS, Tsukamoto T, Majer P, Slusher BS, Rais R. Novotná K, et al. Among authors: mettu vs. J Med Chem. 2023 Nov 23;66(22):15493-15510. doi: 10.1021/acs.jmedchem.3c01681. Epub 2023 Nov 10. J Med Chem. 2023. PMID: 37949450 Free PMC article.

5

Interplay of Breast Cancer Resistance Protein (Bcrp/Abcg2), Sex, and Fed State in Oral Pharmacokinetic Variability of Furosemide in Rats.

Sharma S, Mettu VS, Prasad B. Sharma S, et al. Among authors: mettu vs. Pharmaceutics. 2023 Feb 6;15(2):542. doi: 10.3390/pharmaceutics15020542. Pharmaceutics. 2023. PMID: 36839862 Free PMC article.

6

Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling.

Sharma S, Singh DK, Mettu VS, Yue G, Ahire D, Basit A, Heyward S, Prasad B. Sharma S, et al. Among authors: mettu vs. Mol Pharm. 2023 Mar 6;20(3):1737-1749. doi: 10.1021/acs.molpharmaceut.2c00950. Epub 2023 Feb 15. Mol Pharm. 2023. PMID: 36791335

7

Relevance of Human Aldoketoreductases and Microbial β-Glucuronidases in Testosterone Disposition.

Basit A, Amory JK, Mettu VS, Li CY, Heyward S, Jariwala PB, Redinbo MR, Prasad B. Basit A, et al. Among authors: mettu vs. Drug Metab Dispos. 2023 Apr;51(4):427-435. doi: 10.1124/dmd.122.000975. Epub 2023 Jan 9. Drug Metab Dispos. 2023. PMID: 36623880 Free PMC article.

8

Quantitative Proteomics in Translational Absorption, Distribution, Metabolism, and Excretion and Precision Medicine.

Ahire D, Kruger L, Sharma S, Mettu VS, Basit A, Prasad B. Ahire D, et al. Among authors: mettu vs. Pharmacol Rev. 2022 Jul;74(3):769-796. doi: 10.1124/pharmrev.121.000449. Pharmacol Rev. 2022. PMID: 35738681 Free PMC article. Review.

9

Differential proteomics analysis of JEG-3 and JAR placental cell models and the effect of androgen treatment.

Kruger L, Yue G, Mettu VS, Paquette A, Sathyanarayana S, Prasad B. Kruger L, et al. Among authors: mettu vs. J Steroid Biochem Mol Biol. 2022 Sep;222:106138. doi: 10.1016/j.jsbmb.2022.106138. Epub 2022 Jun 8. J Steroid Biochem Mol Biol. 2022. PMID: 35690242

10

The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized Controlled Trial.

Miller L, Thompson K, Pavlenco C, Mettu VS, Haverkamp H, Skaufel S, Basit A, Prasad B, Larsen J. Miller L, et al. Among authors: mettu vs. Nutrients. 2021 Oct 15;13(10):3620. doi: 10.3390/nu13103620. Nutrients. 2021. PMID: 34684621 Free PMC article. Clinical Trial.

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