Sagare A - Search Results

1

Associations between Vascular Function and Tau PET Are Associated with Global Cognition and Amyloid.

Albrecht D, Isenberg AL, Stradford J, Monreal T, Sagare A, Pachicano M, Sweeney M, Toga A, Zlokovic B, Chui H, Joe E, Schneider L, Conti P, Jann K, Pa J. Albrecht D, et al. Among authors: sagare a. J Neurosci. 2020 Oct 28;40(44):8573-8586. doi: 10.1523/JNEUROSCI.1230-20.2020. Epub 2020 Oct 12. J Neurosci. 2020. PMID: 33046556 Free PMC article.

2

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV. LaRue B, et al. Among authors: sagare a. J Neurosci Methods. 2004 Sep 30;138(1-2):233-42. doi: 10.1016/j.jneumeth.2004.04.026. J Neurosci Methods. 2004. PMID: 15325132

3

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: sagare a. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

4

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV. Deane R, et al. Among authors: sagare a. J Neurosci. 2005 Dec 14;25(50):11495-503. doi: 10.1523/JNEUROSCI.3697-05.2005. J Neurosci. 2005. PMID: 16354907 Free PMC article.

5

Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system.

Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV. Bell RD, et al. J Cereb Blood Flow Metab. 2007 May;27(5):909-18. doi: 10.1038/sj.jcbfm.9600419. Epub 2006 Nov 1. J Cereb Blood Flow Metab. 2007. PMID: 17077814 Free PMC article.

6

Clearance of amyloid-beta by circulating lipoprotein receptors.

Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Sagare A, et al. Nat Med. 2007 Sep;13(9):1029-31. doi: 10.1038/nm1635. Epub 2007 Aug 12. Nat Med. 2007. PMID: 17694066 Free PMC article.

7

The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.

Deane R, Sagare A, Zlokovic BV. Deane R, et al. Among authors: sagare a. Curr Pharm Des. 2008;14(16):1601-5. doi: 10.2174/138161208784705487. Curr Pharm Des. 2008. PMID: 18673201 Free PMC article. Review.

8

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.

Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV. Deane R, et al. Among authors: sagare a. J Clin Invest. 2008 Dec;118(12):4002-13. doi: 10.1172/JCI36663. Epub 2008 Nov 13. J Clin Invest. 2008. PMID: 19033669 Free PMC article.

9

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells.

Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. Bell RD, et al. Among authors: sagare a. Nat Cell Biol. 2009 Feb;11(2):143-53. doi: 10.1038/ncb1819. Epub 2008 Dec 21. Nat Cell Biol. 2009. PMID: 19098903 Free PMC article.

10

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.

Deane R, Bell RD, Sagare A, Zlokovic BV. Deane R, et al. Among authors: sagare a. CNS Neurol Disord Drug Targets. 2009 Mar;8(1):16-30. doi: 10.2174/187152709787601867. CNS Neurol Disord Drug Targets. 2009. PMID: 19275634 Free PMC article. Review.

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