Roland BP - Search Results

1

A Tutorial for Pharmacogenomics Implementation Through End-to-End Clinical Decision Support Based on Ten Years of Experience from PREDICT.

Liu M, Vnencak-Jones CL, Roland BP, Gatto CL, Mathe JL, Just SL, Peterson JF, Van Driest SL, Weitkamp AO. Liu M, et al. Among authors: roland bp. Clin Pharmacol Ther. 2021 Jan;109(1):101-115. doi: 10.1002/cpt.2079. Epub 2020 Nov 15. Clin Pharmacol Ther. 2021. PMID: 33048353 Free PMC article. Review.

2

Impact of Updating Pharmacogenetic Results: Lessons Learned from the PREDICT Program.

Liu M, Van Driest SL, Vnencak-Jones CL, Saucier LAG, Roland BP, Gatto CL, Just SL, Weitkamp AO, Peterson JF. Liu M, et al. Among authors: roland bp. J Pers Med. 2021 Oct 20;11(11):1051. doi: 10.3390/jpm11111051. J Pers Med. 2021. PMID: 34834403 Free PMC article.

3

Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity.

Jain BK, Roland BP, Graham TR. Jain BK, et al. Among authors: roland bp. J Biol Chem. 2020 Dec 25;295(52):17997-18009. doi: 10.1074/jbc.RA120.014794. Epub 2020 Oct 15. J Biol Chem. 2020. PMID: 33060204 Free PMC article.

4

[No title available]

[No authors listed] [No authors listed] PMID: 33453812

5

Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase.

Roland BP, Graham TR. Roland BP, et al. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4460-6. doi: 10.1073/pnas.1525730113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432949 Free PMC article.

6

Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs.

Roland BP, Naito T, Best JT, Arnaiz-Yépez C, Takatsu H, Yu RJ, Shin HW, Graham TR. Roland BP, et al. J Biol Chem. 2019 Feb 8;294(6):1794-1806. doi: 10.1074/jbc.RA118.005876. Epub 2018 Dec 10. J Biol Chem. 2019. PMID: 30530492 Free PMC article.

7

Decoding P4-ATPase substrate interactions.

Roland BP, Graham TR. Roland BP, et al. Crit Rev Biochem Mol Biol. 2016 Nov/Dec;51(6):513-527. doi: 10.1080/10409238.2016.1237934. Epub 2016 Oct 4. Crit Rev Biochem Mol Biol. 2016. PMID: 27696908 Free PMC article. Review.

8

Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.

Roland BP, Richards KR, Hrizo SL, Eicher S, Barile ZJ, Chang TC, Savon G, Bianchi P, Fermo E, Ricerca BM, Tortorolo L, Vockley J, VanDemark AP, Palladino MJ. Roland BP, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2257-2266. doi: 10.1016/j.bbadis.2019.05.002. Epub 2019 May 7. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31075491 Free PMC article.

9

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.

Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ. Roland BP, et al. Biochim Biophys Acta. 2015 Jan;1852(1):61-9. doi: 10.1016/j.bbadis.2014.10.010. Epub 2014 Oct 16. Biochim Biophys Acta. 2015. PMID: 25463631 Free PMC article.

10

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics.

Roland BP, Zeccola AM, Larsen SB, Amrich CG, Talsma AD, Stuchul KA, Heroux A, Levitan ES, VanDemark AP, Palladino MJ. Roland BP, et al. PLoS Genet. 2016 Mar 31;12(3):e1005941. doi: 10.1371/journal.pgen.1005941. eCollection 2016 Mar. PLoS Genet. 2016. PMID: 27031109 Free PMC article.

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