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Discovery of Zika Virus NS2B/NS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage.
Coluccia A, Puxeddu M, Nalli M, Wei CK, Wu YH, Mastrangelo E, Elamin T, Tarantino D, Bugert JJ, Schreiner B, Nolte J, Schwarze F, La Regina G, Lee JC, Silvestri R. Coluccia A, et al. Among authors: mastrangelo e. ACS Med Chem Lett. 2020 Jan 15;11(10):1869-1874. doi: 10.1021/acsmedchemlett.9b00405. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062166 Free PMC article.
Structure-based inhibition of Norovirus RNA-dependent RNA polymerases.
Mastrangelo E, Pezzullo M, Tarantino D, Petazzi R, Germani F, Kramer D, Robel I, Rohayem J, Bolognesi M, Milani M. Mastrangelo E, et al. J Mol Biol. 2012 Jun 8;419(3-4):198-210. doi: 10.1016/j.jmb.2012.03.008. Epub 2012 Mar 21. J Mol Biol. 2012. PMID: 22446684
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions.
Cannalire R, Tarantino D, Piorkowski G, Carletti T, Massari S, Felicetti T, Barreca ML, Sabatini S, Tabarrini O, Marcello A, Milani M, Cecchetti V, Mastrangelo E, Manfroni G, Querat G. Cannalire R, et al. Among authors: mastrangelo e. Antiviral Res. 2019 Jul;167:6-12. doi: 10.1016/j.antiviral.2019.03.004. Epub 2019 Mar 6. Antiviral Res. 2019. PMID: 30849420
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase.
Cannalire R, Ki Chan KW, Burali MS, Gwee CP, Wang S, Astolfi A, Massari S, Sabatini S, Tabarrini O, Mastrangelo E, Barreca ML, Cecchetti V, Vasudevan SG, Manfroni G. Cannalire R, et al. Among authors: mastrangelo e. ACS Med Chem Lett. 2020 Mar 19;11(5):773-782. doi: 10.1021/acsmedchemlett.9b00619. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435384 Free PMC article.
72 results