Yan R - Search Results

1

β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification.

Hampel H, Lista S, Vanmechelen E, Zetterberg H, Giorgi FS, Galgani A, Blennow K, Caraci F, Das B, Yan R, Vergallo A; Alzheimer’s Precision Medicine Initiative (APMI). Hampel H, et al. Among authors: yan r. Alzheimers Res Ther. 2020 Oct 16;12(1):130. doi: 10.1186/s13195-020-00686-3. Alzheimers Res Ther. 2020. PMID: 33066807 Free PMC article. Review.

2

Inhibition of BACE1 for therapeutic use in Alzheimer's disease.

Luo X, Yan R. Luo X, et al. Among authors: yan r. Int J Clin Exp Pathol. 2010 Jul 8;3(6):618-28. Int J Clin Exp Pathol. 2010. PMID: 20661410 Free PMC article. Review.

3

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.

Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Sharoar MG, et al. Among authors: yan r. Mol Psychiatry. 2016 Sep;21(9):1263-71. doi: 10.1038/mp.2015.181. Epub 2015 Dec 1. Mol Psychiatry. 2016. PMID: 26619807 Free PMC article.

4

Role of BACE1 in Alzheimer's synaptic function.

Das B, Yan R. Das B, et al. Among authors: yan r. Transl Neurodegener. 2017 Aug 30;6:23. doi: 10.1186/s40035-017-0093-5. eCollection 2017. Transl Neurodegener. 2017. PMID: 28855981 Free PMC article. Review.

5

BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.

Hu X, Das B, Hou H, He W, Yan R. Hu X, et al. Among authors: yan r. J Exp Med. 2018 Mar 5;215(3):927-940. doi: 10.1084/jem.20171831. Epub 2018 Feb 14. J Exp Med. 2018. PMID: 29444819 Free PMC article.

6

The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease.

Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. Wang C, et al. Among authors: yan r. Brain Pathol. 2019 Jul;29(4):530-543. doi: 10.1111/bpa.12691. Epub 2019 Jan 28. Brain Pathol. 2019. PMID: 30515907 Free PMC article.

7

A Close Look at BACE1 Inhibitors for Alzheimer's Disease Treatment.

Das B, Yan R. Das B, et al. Among authors: yan r. CNS Drugs. 2019 Mar;33(3):251-263. doi: 10.1007/s40263-019-00613-7. CNS Drugs. 2019. PMID: 30830576 Free PMC article. Review.

8

The β-Secretase BACE1 in Alzheimer's Disease.

Hampel H, Vassar R, De Strooper B, Hardy J, Willem M, Singh N, Zhou J, Yan R, Vanmechelen E, De Vos A, Nisticò R, Corbo M, Imbimbo BP, Streffer J, Voytyuk I, Timmers M, Tahami Monfared AA, Irizarry M, Albala B, Koyama A, Watanabe N, Kimura T, Yarenis L, Lista S, Kramer L, Vergallo A. Hampel H, et al. Among authors: yan r. Biol Psychiatry. 2021 Apr 15;89(8):745-756. doi: 10.1016/j.biopsych.2020.02.001. Epub 2020 Feb 13. Biol Psychiatry. 2021. PMID: 32223911 Free PMC article. Review.

9

Activity of Alzheimer's γ-secretase is linked to changes of interferon-induced transmembrane proteins (IFITM) in innate immunity.

Yao AY, Yan R. Yao AY, et al. Among authors: yan r. Mol Neurodegener. 2020 Nov 12;15(1):69. doi: 10.1186/s13024-020-00417-0. Mol Neurodegener. 2020. PMID: 33183335 Free PMC article.

10

Metabotropic Glutamate Receptors in Alzheimer's Disease Synaptic Dysfunction: Therapeutic Opportunities and Hope for the Future.

Srivastava A, Das B, Yao AY, Yan R. Srivastava A, et al. Among authors: yan r. J Alzheimers Dis. 2020;78(4):1345-1361. doi: 10.3233/JAD-201146. J Alzheimers Dis. 2020. PMID: 33325389 Free PMC article. Review.

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