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Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.
Lim WW, Corden B, Ng B, Vanezis K, D'Agostino G, Widjaja AA, Song WH, Xie C, Su L, Kwek XY, Tee NGZ, Dong J, Ko NSJ, Wang M, Pua CJ, Jamal MH, Soh B, Viswanathan S, Schafer S, Cook SA. Lim WW, et al. Among authors: tee ngz. Sci Rep. 2020 Oct 20;10(1):17853. doi: 10.1038/s41598-020-74944-7. Sci Rep. 2020. PMID: 33082445 Free PMC article.
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome.
Lim WW, Dong J, Ng B, Widjaja AA, Xie C, Su L, Kwek XY, Tee NGZ, Jian Pua C, Schafer S, Viswanathan S, Cook SA. Lim WW, et al. Among authors: tee ngz. Circ Res. 2022 Mar 4;130(5):728-740. doi: 10.1161/CIRCRESAHA.121.320381. Epub 2022 Feb 9. Circ Res. 2022. PMID: 35135328 Free article.
Titin-truncating variants affect heart function in disease cohorts and the general population.
Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA. Schafer S, et al. Nat Genet. 2017 Jan;49(1):46-53. doi: 10.1038/ng.3719. Epub 2016 Nov 21. Nat Genet. 2017. PMID: 27869827 Free PMC article.
Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.
Ong SB, Kwek XY, Katwadi K, Hernandez-Resendiz S, Crespo-Avilan GE, Ismail NI, Lin YH, Yap EP, Lim SY, Ja KPMM, Ramachandra CJA, Tee N, Toh JJ, Shim W, Wong P, Cabrera-Fuentes HA, Hausenloy DJ. Ong SB, et al. Int J Mol Sci. 2019 Aug 15;20(16):3972. doi: 10.3390/ijms20163972. Int J Mol Sci. 2019. PMID: 31443187 Free PMC article.
19 results