Greupink R - Search Results

1

Toxicity of anticancer drugs in human placental tissue explants and trophoblast cell lines.

Eliesen GAM, van Hove H, Meijer MH, van den Broek PHH, Pertijs J, Roeleveld N, van Drongelen J, Russel FGM, Greupink R. Eliesen GAM, et al. Among authors: greupink r. Arch Toxicol. 2021 Feb;95(2):557-571. doi: 10.1007/s00204-020-02925-w. Epub 2020 Oct 20. Arch Toxicol. 2021. PMID: 33083868 Free PMC article.

2

Demystifying physiologically based pharmacokinetic modelling among non-modelers towards model-informed medicine use in under-served populations.

Freriksen J, van der Heijden J, de Hoop-Sommen M, Johnson T, Yeo KR, Kerwash E, Cole S, Nooney J, Greupink R, Zhao P, de Wildt S. Freriksen J, et al. Among authors: greupink r. Gates Open Res. 2023 Oct 26;7:128. doi: 10.12688/gatesopenres.14896.1. eCollection 2023. Gates Open Res. 2023. PMID: 39035470 Free PMC article.

3

Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Greupink R, Dillen L, Monshouwer M, Huisman MT, Russel FG. Greupink R, et al. Eur J Pharm Sci. 2011 Nov 20;44(4):487-96. doi: 10.1016/j.ejps.2011.09.009. Epub 2011 Sep 16. Eur J Pharm Sci. 2011. PMID: 21945488

4

Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

Wittgen HG, Greupink R, van den Heuvel JJ, van den Broek PH, Dinter-Heidorn H, Koenderink JB, Russel FG. Wittgen HG, et al. Among authors: greupink r. Mol Pharm. 2012 May 7;9(5):1351-60. doi: 10.1021/mp200617z. Epub 2012 Mar 28. Mol Pharm. 2012. PMID: 22428727

5

In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.

Greupink R, Nabuurs SB, Zarzycka B, Verweij V, Monshouwer M, Huisman MT, Russel FG. Greupink R, et al. Toxicol Sci. 2012 Sep;129(1):35-48. doi: 10.1093/toxsci/kfs188. Epub 2012 May 28. Toxicol Sci. 2012. PMID: 22641618

6

Interaction of digitalis-like compounds with p-glycoprotein.

Gozalpour E, Wittgen HG, van den Heuvel JJ, Greupink R, Russel FG, Koenderink JB. Gozalpour E, et al. Among authors: greupink r. Toxicol Sci. 2013 Feb;131(2):502-11. doi: 10.1093/toxsci/kfs307. Epub 2012 Oct 26. Toxicol Sci. 2013. PMID: 23104431

7

Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions.

Greupink R, Schreurs M, Benne MS, Huisman MT, Russel FG. Greupink R, et al. Eur J Pharm Sci. 2013 Aug 16;49(5):819-28. doi: 10.1016/j.ejps.2013.06.009. Epub 2013 Jun 24. Eur J Pharm Sci. 2013. PMID: 23806476

8

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.

El-Sheikh AA, Greupink R, Wortelboer HM, van den Heuvel JJ, Schreurs M, Koenderink JB, Masereeuw R, Russel FG. El-Sheikh AA, et al. Among authors: greupink r. Transl Res. 2013 Dec;162(6):398-409. doi: 10.1016/j.trsl.2013.08.003. Epub 2013 Sep 12. Transl Res. 2013. PMID: 24036158

9

In silico identification and in vitro validation of potential cholestatic compounds through 3D ligand-based pharmacophore modeling of BSEP inhibitors.

Ritschel T, Hermans SM, Schreurs M, van den Heuvel JJ, Koenderink JB, Greupink R, Russel FG. Ritschel T, et al. Among authors: greupink r. Chem Res Toxicol. 2014 May 19;27(5):873-81. doi: 10.1021/tx5000393. Epub 2014 Apr 23. Chem Res Toxicol. 2014. PMID: 24713091

10

Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.

Gozalpour E, Greupink R, Wortelboer HM, Bilos A, Schreurs M, Russel FG, Koenderink JB. Gozalpour E, et al. Among authors: greupink r. Mol Pharm. 2014 Jun 2;11(6):1844-55. doi: 10.1021/mp400699p. Epub 2014 May 6. Mol Pharm. 2014. PMID: 24754247

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