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SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures.
Tlemsani C, Pongor L, Elloumi F, Girard L, Huffman KE, Roper N, Varma S, Luna A, Rajapakse VN, Sebastian R, Kohn KW, Krushkal J, Aladjem MI, Teicher BA, Meltzer PS, Reinhold WC, Minna JD, Thomas A, Pommier Y. Tlemsani C, et al. Among authors: sebastian r. Cell Rep. 2020 Oct 20;33(3):108296. doi: 10.1016/j.celrep.2020.108296. Cell Rep. 2020. PMID: 33086069 Free PMC article.
Dynamics of replication origin over-activation.
Fu H, Redon CE, Thakur BL, Utani K, Sebastian R, Jang SM, Gross JM, Mosavarpour S, Marks AB, Zhuang SZ, Lazar SB, Rao M, Mencer ST, Baris AM, Pongor LS, Aladjem MI. Fu H, et al. Among authors: sebastian r. Nat Commun. 2021 Jun 8;12(1):3448. doi: 10.1038/s41467-021-23835-0. Nat Commun. 2021. PMID: 34103496 Free PMC article.
Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy.
Thakur BL, Baris AM, Fu H, Redon CE, Pongor LS, Mosavarpour S, Gross JM, Jang SM, Sebastian R, Utani K, Jenkins LM, Indig FE, Aladjem MI. Thakur BL, et al. Among authors: sebastian r. Nucleic Acids Res. 2022 May 20;50(9):5111-5128. doi: 10.1093/nar/gkac299. Nucleic Acids Res. 2022. PMID: 35524559 Free PMC article.
Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities.
Desai P, Takahashi N, Kumar R, Nichols S, Malin J, Hunt A, Schultz C, Cao Y, Tillo D, Nousome D, Chauhan L, Sciuto L, Jordan K, Rajapakse V, Tandon M, Lissa D, Zhang Y, Kumar S, Pongor L, Singh A, Schroder B, Sharma AK, Chang T, Vilimas R, Pinkiert D, Graham C, Butcher D, Warner A, Sebastian R, Mahon M, Baker K, Cheng J, Berger A, Lake R, Abel M, Krishnamurthy M, Chrisafis G, Fitzgerald P, Nirula M, Goyal S, Atkinson D, Bateman NW, Abulez T, Nair G, Apolo A, Guha U, Karim B, El Meskini R, Ohler ZW, Jolly MK, Schaffer A, Ruppin E, Kleiner D, Miettinen M, Brown GT, Hewitt S, Conrads T, Thomas A. Desai P, et al. Among authors: sebastian r. Cell Rep Med. 2024 Jun 18;5(6):101610. doi: 10.1016/j.xcrm.2024.101610. Cell Rep Med. 2024. PMID: 38897168 Free PMC article.
Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4.
Mizunuma M, Redon CE, Saha LK, Tran AD, Dhall A, Sebastian R, Taniyama D, Kruhlak MJ, Reinhold WC, Takebe N, Pommier Y. Mizunuma M, et al. Among authors: sebastian r. Cancer Res Commun. 2024 Aug 1;4(8):2101-2111. doi: 10.1158/2767-9764.CRC-24-0093. Cancer Res Commun. 2024. PMID: 39041239 Free PMC article.
Transcription-associated events affecting genomic integrity.
Sebastian R, Oberdoerffer P. Sebastian R, et al. Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731):20160288. doi: 10.1098/rstb.2016.0288. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28847825 Free PMC article. Review.
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
Kim J, Sturgill D, Sebastian R, Khurana S, Tran AD, Edwards GB, Kruswick A, Burkett S, Hosogane EK, Hannon WW, Weyemi U, Bonner WM, Luger K, Oberdoerffer P. Kim J, et al. Among authors: sebastian r. Mol Cell. 2018 Jan 4;69(1):36-47.e7. doi: 10.1016/j.molcel.2017.11.021. Epub 2017 Dec 14. Mol Cell. 2018. PMID: 29249653 Free PMC article.
352 results