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Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Balakrishnan I, Danis E, Pierce A, Madhavan K, Wang D, Dahl N, Sanford B, Birks DK, Davidson N, Metselaar DS, Meel MH, Lemma R, Donson A, Vijmasi T, Katagi H, Sola I, Fosmire S, Alimova I, Steiner J, Gilani A, Hulleman E, Serkova NJ, Hashizume R, Hawkins C, Carcaboso AM, Gupta N, Monje M, Jabado N, Jones K, Foreman N, Green A, Vibhakar R, Venkataraman S. Balakrishnan I, et al. Among authors: green a. Cell Rep. 2020 Oct 20;33(3):108286. doi: 10.1016/j.celrep.2020.108286. Cell Rep. 2020. PMID: 33086074 Free PMC article.
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Mulcahy Levy JM, Zahedi S, Griesinger AM, Morin A, Davies KD, Aisner DL, Kleinschmidt-DeMasters BK, Fitzwalter BE, Goodall ML, Thorburn J, Amani V, Donson AM, Birks DK, Mirsky DM, Hankinson TC, Handler MH, Green AL, Vibhakar R, Foreman NK, Thorburn A. Mulcahy Levy JM, et al. Among authors: green al. Elife. 2017 Jan 17;6:e19671. doi: 10.7554/eLife.19671. Elife. 2017. PMID: 28094001 Free PMC article.
Tumor treating fields in pediatric high-grade glioma.
Green AL, Mulcahy Levy JM, Vibhakar R, Hemenway M, Madden J, Foreman N, Dorris K. Green AL, et al. Childs Nerv Syst. 2017 Jul;33(7):1043-1045. doi: 10.1007/s00381-017-3431-0. Epub 2017 May 3. Childs Nerv Syst. 2017. PMID: 28470383
Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Flannery PC, DeSisto JA, Amani V, Venkataraman S, Lemma RT, Prince EW, Donson A, Moroze EE, Hoffman L, Levy JMM, Foreman N, Vibhakar R, Green AL. Flannery PC, et al. Among authors: green al. Oncol Rep. 2018 Feb;39(2):455-464. doi: 10.3892/or.2017.6122. Epub 2017 Nov 29. Oncol Rep. 2018. PMID: 29207163 Free PMC article.
Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma.
DeSisto JA, Flannery P, Lemma R, Pathak A, Mestnik S, Philips N, Bales NJ, Kashyap T, Moroze E, Venkataraman S, Kung AL, Carter BD, Landesman Y, Vibhakar R, Green AL. DeSisto JA, et al. Among authors: green al. Mol Cancer Ther. 2020 Feb;19(2):540-551. doi: 10.1158/1535-7163.MCT-18-1319. Epub 2019 Oct 8. Mol Cancer Ther. 2020. PMID: 31594826 Free PMC article.
Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Lake JA, Donson AM, Prince E, Davies KD, Nellan A, Green AL, Mulcahy Levy J, Dorris K, Vibhakar R, Hankinson TC, Foreman NK, Ewalt MD, Kleinschmidt-DeMasters BK, Hoffman LM, Gilani A. Lake JA, et al. Among authors: green al. Pediatr Blood Cancer. 2020 Jan;67(1):e28028. doi: 10.1002/pbc.28028. Epub 2019 Oct 8. Pediatr Blood Cancer. 2020. PMID: 31595628 Free PMC article.
6,882 results