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Page 1
Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site.
Fowler JC, King C, Bryant C, Hall MWJ, Sood R, Ong SH, Earp E, Fernandez-Antoran D, Koeppel J, Dentro SC, Shorthouse D, Durrani A, Fife K, Rytina E, Milne D, Roshan A, Mahububani K, Saeb-Parsy K, Hall BA, Gerstung M, Jones PH. Fowler JC, et al. Among authors: ong sh. Cancer Discov. 2021 Feb;11(2):340-361. doi: 10.1158/2159-8290.CD-20-1092. Epub 2020 Oct 21. Cancer Discov. 2021. PMID: 33087317 Free PMC article.
Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong SH, Nagy T, Cagan A, Goulding D, Klein AM, Hall BA, Jones PH. Murai K, et al. Among authors: ong sh. Cell Stem Cell. 2018 Nov 1;23(5):687-699.e8. doi: 10.1016/j.stem.2018.08.017. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269904 Free PMC article.
Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.
Fernandez-Antoran D, Piedrafita G, Murai K, Ong SH, Herms A, Frezza C, Jones PH. Fernandez-Antoran D, et al. Among authors: ong sh. Cell Stem Cell. 2019 Sep 5;25(3):329-341.e6. doi: 10.1016/j.stem.2019.06.011. Epub 2019 Jul 18. Cell Stem Cell. 2019. PMID: 31327664 Free PMC article.
Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PH. Colom B, et al. Among authors: ong sh. Nature. 2021 Oct;598(7881):510-514. doi: 10.1038/s41586-021-03965-7. Epub 2021 Oct 13. Nature. 2021. PMID: 34646013 Free PMC article.
Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus.
Herms A, Colom B, Piedrafita G, Kalogeropoulou A, Banerjee U, King C, Abby E, Murai K, Caseda I, Fernandez-Antoran D, Ong SH, Hall MWJ, Bryant C, Sood RK, Fowler JC, Pol A, Frezza C, Vanhaesebroeck B, Jones PH. Herms A, et al. Among authors: ong sh. Nat Genet. 2024 Oct;56(10):2144-2157. doi: 10.1038/s41588-024-01891-8. Epub 2024 Aug 21. Nat Genet. 2024. PMID: 39169259 Free PMC article.
Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium.
Herms A, Fernandez-Antoran D, Alcolea MP, Kalogeropoulou A, Banerjee U, Piedrafita G, Abby E, Valverde-Lopez JA, Ferreira IS, Caseda I, Bejar MT, Dentro SC, Vidal-Notari S, Ong SH, Colom B, Murai K, King C, Mahbubani K, Saeb-Parsy K, Lowe AR, Gerstung M, Jones PH. Herms A, et al. Among authors: ong sh. Nat Genet. 2024 Oct;56(10):2158-2173. doi: 10.1038/s41588-024-01875-8. Epub 2024 Sep 23. Nat Genet. 2024. PMID: 39313617 Free PMC article.
RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing.
Gu M, Zwiebel M, Ong SH, Boughton N, Nomdedeu J, Basheer F, Nannya Y, Quiros PM, Ogawa S, Cazzola M, Rad R, Butler AP, Vijayabaskar MS, Vassiliou GS. Gu M, et al. Among authors: ong sh. Haematologica. 2020 Jun;105(6):e290-e293. doi: 10.3324/haematol.2019.230821. Epub 2019 Oct 24. Haematologica. 2020. PMID: 31649132 Free PMC article. No abstract available.
257 results