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P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition.
Vázquez-Rosa E, Shin MK, Dhar M, Chaubey K, Cintrón-Pérez CJ, Tang X, Liao X, Miller E, Koh Y, Barker S, Franke K, Crosby DR, Schroeder R, Emery J, Yin TC, Fujioka H, Reynolds JD, Harper MM, Jain MK, Pieper AA. Vázquez-Rosa E, et al. Among authors: cintron perez cj. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27667-27675. doi: 10.1073/pnas.2010430117. Epub 2020 Oct 21. Proc Natl Acad Sci U S A. 2020. PMID: 33087571 Free PMC article.
Neuroprotective efficacy of P7C3 compounds in primate hippocampus.
Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA. Bauman MD, et al. Among authors: cintron perez cj. Transl Psychiatry. 2018 Sep 26;8(1):202. doi: 10.1038/s41398-018-0244-1. Transl Psychiatry. 2018. PMID: 30258178 Free PMC article.
Neuroprotective Efficacy of a Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury.
Vázquez-Rosa E, Watson MR, Sahn JJ, Hodges TR, Schroeder RE, Cintrón-Pérez CJ, Shin MK, Yin TC, Emery JL, Martin SF, Liebl DJ, Pieper AA. Vázquez-Rosa E, et al. Among authors: cintron perez cj. ACS Chem Neurosci. 2019 Mar 20;10(3):1595-1602. doi: 10.1021/acschemneuro.8b00543. Epub 2018 Dec 3. ACS Chem Neurosci. 2019. PMID: 30421909 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35108890
(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.
Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA. Voorhees JR, et al. Biol Psychiatry. 2018 Oct 1;84(7):488-498. doi: 10.1016/j.biopsych.2017.10.023. Epub 2017 Nov 6. Biol Psychiatry. 2018. PMID: 29246437 Free PMC article.
14 results