Miller GP - Search Results

1

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics.

Pinson AO, Pouncey DL, Schleiff MA, Fantegrossi WE, Prather PL, Radominska-Pandya A, Boysen G, Miller GP. Pinson AO, et al. Among authors: miller gp. Molecules. 2020 Oct 20;25(20):4820. doi: 10.3390/molecules25204820. Molecules. 2020. PMID: 33092129 Free PMC article.

2

CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling.

Collom SL, Jamakhandi AP, Tackett AJ, Radominska-Pandya A, Miller GP. Collom SL, et al. Among authors: miller gp. Arch Biochem Biophys. 2007 Mar 1;459(1):59-69. doi: 10.1016/j.abb.2006.10.028. Epub 2006 Nov 2. Arch Biochem Biophys. 2007. PMID: 17222385 Free PMC article.

3

Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.

Zielinska A, Lichti CF, Bratton S, Mitchell NC, Gallus-Zawada A, Le VH, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Zielinska A, et al. Among authors: miller gp. J Pharmacol Exp Ther. 2008 Jan;324(1):139-48. doi: 10.1124/jpet.107.129858. Epub 2007 Oct 5. J Pharmacol Exp Ther. 2008. PMID: 17921187 Free PMC article.

4

The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.

Xiong Y, Patana AS, Miley MJ, Zielinska AK, Bratton SM, Miller GP, Goldman A, Finel M, Redinbo MR, Radominska-Pandya A. Xiong Y, et al. Among authors: miller gp. Drug Metab Dispos. 2008 Mar;36(3):517-22. doi: 10.1124/dmd.107.016469. Epub 2007 Nov 29. Drug Metab Dispos. 2008. PMID: 18048489 Free PMC article.

5

Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.

Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Miller GP, et al. Drug Metab Dispos. 2008 Nov;36(11):2211-8. doi: 10.1124/dmd.108.022863. Epub 2008 Aug 25. Drug Metab Dispos. 2008. PMID: 18725508 Free PMC article.

6

Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.

Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radomińska-Pandya A, Moran JH. Mazur A, et al. Among authors: miller gp. Drug Metab Dispos. 2009 Jul;37(7):1496-504. doi: 10.1124/dmd.109.026898. Epub 2009 Apr 1. Drug Metab Dispos. 2009. PMID: 19339377 Free PMC article.

7

Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans.

Miller GP, Jones DR, Sullivan SZ, Mazur A, Owen SN, Mitchell NC, Radominska-Pandya A, Moran JH. Miller GP, et al. Chem Res Toxicol. 2009 Jul;22(7):1239-45. doi: 10.1021/tx900031z. Chem Res Toxicol. 2009. PMID: 19408964 Free PMC article.

8

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

Jones DR, Kim SY, Boysen G, Yun CH, Miller GP. Jones DR, et al. Among authors: miller gp. Drug Metab Lett. 2010 Dec;4(4):213-9. doi: 10.2174/187231210792928242. Drug Metab Lett. 2010. PMID: 20615193

9

Novel multi-mode ultra performance liquid chromatography-tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma.

Jones DR, Boysen G, Miller GP. Jones DR, et al. Among authors: miller gp. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879(15-16):1056-62. doi: 10.1016/j.jchromb.2011.03.022. Epub 2011 Mar 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21470921

10

CYP2E1 metabolism of styrene involves allostery.

Hartman JH, Boysen G, Miller GP. Hartman JH, et al. Among authors: miller gp. Drug Metab Dispos. 2012 Oct;40(10):1976-83. doi: 10.1124/dmd.112.046698. Epub 2012 Jul 17. Drug Metab Dispos. 2012. PMID: 22807108 Free PMC article.

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