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Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds.
Cosentino G, Dichiara M, Ambrosio FA, Leotta CG, Costa G, Procopio F, Costanzo G, Raffa A, Artacho-Cordón A, Ruiz-Cantero MC, Pasquinucci L, Marrazzo A, Pitari GM, Cobos EJ, Alcaro S, Amata E. Cosentino G, et al. Among authors: pitari gm. Eur J Med Chem. 2025 Jan 5;281:117037. doi: 10.1016/j.ejmech.2024.117037. Epub 2024 Nov 10. Eur J Med Chem. 2025. PMID: 39547082 Free article.
Haloperidol Metabolite II Valproate Ester (S)-(-)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma.
Barbaraci C, Giurdanella G, Leotta CG, Longo A, Amata E, Dichiara M, Pasquinucci L, Turnaturi R, Prezzavento O, Cacciatore I, Zuccarello E, Lupo G, Pitari GM, Anfuso CD, Marrazzo A. Barbaraci C, et al. Among authors: pitari gm. J Med Chem. 2021 Sep 23;64(18):13622-13632. doi: 10.1021/acs.jmedchem.1c00995. Epub 2021 Sep 3. J Med Chem. 2021. PMID: 34477381 Free PMC article.
Novel sigma 1-antagonists with cis-(+)-normetazocine scaffold: synthesis, molecular modeling, and antinociceptive effect.
Costanzo G, Cosentino G, Grasso M, Patamia V, Zuccalà S, Coco A, Novello E, Al-Khrasani M, Morrone R, Pitari GM, Amata E, Marrazzo A, Rescifina A, Pasquinucci L, Parenti C. Costanzo G, et al. Among authors: pitari gm. RSC Med Chem. 2024 Nov 29. doi: 10.1039/d4md00397g. Online ahead of print. RSC Med Chem. 2024. PMID: 39777289 Free PMC article.
Imidazole-pyridine hybrids as potent anti-cancer agents.
Aruchamy B, Drago C, Russo V, Pitari GM, Ramani P, Aneesh TP, Benny S, Vishnu VR. Aruchamy B, et al. Among authors: pitari gm. Eur J Pharm Sci. 2023 Jan 1;180:106323. doi: 10.1016/j.ejps.2022.106323. Epub 2022 Nov 4. Eur J Pharm Sci. 2023. PMID: 36336277 Free article.
44 results