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Page 1
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.
Khawaja H, Campbell A, Roberts JZ, Javadi A, O'Reilly P, McArt D, Allen WL, Majkut J, Rehm M, Bardelli A, Di Nicolantonio F, Scott CJ, Kennedy R, Vitale N, Harrison T, Sansom OJ, Longley DB, Evergren E, Van Schaeybroeck S. Khawaja H, et al. Among authors: kennedy r. Cell Death Dis. 2020 Oct 29;11(10):930. doi: 10.1038/s41419-020-03131-3. Cell Death Dis. 2020. PMID: 33122623 Free PMC article.
TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
D'Costa ZC, Higgins C, Ong CW, Irwin GW, Boyle D, McArt DG, McCloskey K, Buckley NE, Crawford NT, Thiagarajan L, Murray JT, Kennedy RD, Mulligan KA, Harkin DP, Waugh DJ, Scott CJ, Salto-Tellez M, Williams R, Mullan PB. D'Costa ZC, et al. Among authors: kennedy rd. Oncotarget. 2014 Mar 30;5(6):1609-20. doi: 10.18632/oncotarget.1707. Oncotarget. 2014. PMID: 24742492 Free PMC article.
PICan: An integromics framework for dynamic cancer biomarker discovery.
McArt DG, Blayney JK, Boyle DP, Irwin GW, Moran M, Hutchinson RA, Bankhead P, Kieran D, Wang Y, Dunne PD, Kennedy RD, Mullan PB, Harkin DP, Catherwood MA, James JA, Salto-Tellez M, Hamilton PW. McArt DG, et al. Mol Oncol. 2015 Jun;9(6):1234-40. doi: 10.1016/j.molonc.2015.02.002. Epub 2015 Mar 4. Mol Oncol. 2015. PMID: 25814194 Free PMC article.
Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program.
Lawler M, Gavin A, Salto-Tellez M, Kennedy RD, Van Schaeybroeck S, Wilson RH, Harkin DP, Grayson M, Boyd RE, Hamilton PW, McArt DG, James J, Robson T, Ladner RD, Prise KM, O'Sullivan JM, Harrison T, Murray L, Johnston PG, Waugh DJ. Lawler M, et al. Cancer. 2016 Mar 1;122(5):664-73. doi: 10.1002/cncr.29814. Epub 2015 Dec 22. Cancer. 2016. PMID: 26695702 Free PMC article.
A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer.
Wilkinson RDA, Burden RE, McDowell SH, McArt DG, McQuaid S, Bingham V, Williams R, Cox ÓT, O'Connor R, McCabe N, Kennedy RD, Buckley NE, Scott CJ. Wilkinson RDA, et al. Among authors: kennedy rd. J Oncol. 2019 Jun 27;2019:3980273. doi: 10.1155/2019/3980273. eCollection 2019. J Oncol. 2019. PMID: 31346333 Free PMC article.
Defining the molecular evolution of extrauterine high grade serous carcinoma.
Beirne JP, McArt DG, Roddy A, McDermott C, Ferris J, Buckley NE, Coulter P, McCabe N, Eddie SL, Dunne PD, O'Reilly P, Gilmore A, Feeney L, Ewing DL, Drapkin RI, Salto-Tellez M, Kennedy RD, Harley IJG, McCluggage WG, Mullan PB. Beirne JP, et al. Gynecol Oncol. 2019 Nov;155(2):305-317. doi: 10.1016/j.ygyno.2019.08.029. Epub 2019 Sep 4. Gynecol Oncol. 2019. PMID: 31493898
In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer.
Malla SB, Fisher DJ, Domingo E, Blake A, Hassanieh S, Redmond KL, Richman SD, Youdell M, Walker SM, Logan GE, Chatzipli A, Amirkhah R, Humphries MP, Craig SG, McDermott U, Seymour MT, Morton DG, Quirke P, West NP, Salto-Tellez M, Kennedy RD, Johnston PG, Tomlinson I, Koelzer VH, Campo L, Kaplan RS, Longley DB, Lawler M, Maughan TS, Brown LC, Dunne PD; S:CORT consortium. Malla SB, et al. Among authors: kennedy rd. Clin Cancer Res. 2021 Jan 1;27(1):288-300. doi: 10.1158/1078-0432.CCR-20-3237. Epub 2020 Oct 7. Clin Cancer Res. 2021. PMID: 33028592 Free PMC article.
USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.
Jurisic A, Sung PJ, Wappett M, Daubriac J, Lobb IT, Kung WW, Crawford N, Page N, Cassidy E, Feutren-Burton S, Rountree JSS, Helm MD, O'Dowd CR, Kennedy RD, Gavory G, Cranston AN, Longley DB, Jacq X, Harrison T. Jurisic A, et al. Among authors: kennedy rd. Clin Transl Med. 2024 Apr;14(4):e1648. doi: 10.1002/ctm2.1648. Clin Transl Med. 2024. PMID: 38602256 Free PMC article.
Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma.
Stevenson L, Cairns L, Li X, Jammula S, Taylor H, Douglas R, McCabe N, Gavory G, Jacq X, Fitzgerald RC, Kennedy RD, Harrison T, Turkington RC. Stevenson L, et al. Among authors: kennedy rd. Sci Rep. 2024 Dec 30;14(1):32121. doi: 10.1038/s41598-024-83912-4. Sci Rep. 2024. PMID: 39739112 Free PMC article.
2,921 results