Menon V - Search Results

1

Design, synthesis, and computational validation of novel compounds selectively targeting HER2-expressing breast cancer.

Elseginy SA, Hamdy R, Menon V, Almehdi AM, El-Awady R, Soliman SSM. Elseginy SA, et al. Among authors: menon v. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127658. doi: 10.1016/j.bmcl.2020.127658. Epub 2020 Oct 29. Bioorg Med Chem Lett. 2020. PMID: 33130288

2

Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells.

El-Awady RA, Semreen MH, Saber-Ayad MM, Cyprian F, Menon V, Al-Tel TH. El-Awady RA, et al. Among authors: menon v. DNA Repair (Amst). 2016 Jan;37:1-11. doi: 10.1016/j.dnarep.2015.10.004. Epub 2015 Nov 4. DNA Repair (Amst). 2016. PMID: 26590797

3

Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types.

Vazhappilly CG, Saleh E, Ramadan W, Menon V, Al-Azawi AM, Tarazi H, Abdu-Allah H, El-Shorbagi AN, El-Awady R. Vazhappilly CG, et al. Among authors: menon v. Invest New Drugs. 2019 Apr;37(2):252-261. doi: 10.1007/s10637-018-0626-5. Epub 2018 Jun 27. Invest New Drugs. 2019. PMID: 29947013

4

Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy.

Ramadan WS, Vazhappilly CG, Saleh EM, Menon V, AlAzawi AM, El-Serafi AT, Mansour W, El-Awady R. Ramadan WS, et al. Among authors: menon v. Cancers (Basel). 2018 Dec 21;11(1):13. doi: 10.3390/cancers11010013. Cancers (Basel). 2018. PMID: 30583472 Free PMC article.

5

DNA-dependent protein kinase: Epigenetic alterations and the role in genomic stability of cancer.

George VC, Ansari SA, Chelakkot VS, Chelakkot AL, Chelakkot C, Menon V, Ramadan W, Ethiraj KR, El-Awady R, Mantso T, Mitsiogianni M, Panagiotidis MI, Dellaire G, Vasantha Rupasinghe HP. George VC, et al. Among authors: menon v. Mutat Res Rev Mutat Res. 2019 Apr-Jun;780:92-105. doi: 10.1016/j.mrrev.2018.06.001. Epub 2018 Jun 19. Mutat Res Rev Mutat Res. 2019. PMID: 31395353 Review.

6

Induction of DNA damage, apoptosis and cell cycle perturbation mediate cytotoxic activity of new 5-aminosalicylate-4-thiazolinone hybrid derivatives.

S Ramadan W, Saleh EM, Menon V, Vazhappilly CG, Abdu-Allah HHM, El-Shorbagi AA, Mansour W, El-Awady R. S Ramadan W, et al. Among authors: menon v. Biomed Pharmacother. 2020 Nov;131:110571. doi: 10.1016/j.biopha.2020.110571. Epub 2020 Aug 28. Biomed Pharmacother. 2020. PMID: 32861966 Free article.

7

Natural compound catechol induces DNA damage, apoptosis, and G1 cell cycle arrest in breast cancer cells.

Vazhappilly CG, Hodeify R, Siddiqui SS, Laham AJ, Menon V, El-Awady R, Matar R, Merheb M, Marton J, Al Zouabi HAK, Radhakrishnan R. Vazhappilly CG, et al. Among authors: menon v. Phytother Res. 2021 Apr;35(4):2185-2199. doi: 10.1002/ptr.6970. Epub 2020 Dec 7. Phytother Res. 2021. PMID: 33289235

8

Discovery of novel class of histone deacetylase inhibitors as potential anticancer agents.

El-Awady R, Saleh E, Hamoudi R, Ramadan WS, Mazitschek R, Nael MA, Elokely KM, Abou-Gharbia M, Childers WE, Srinivasulu V, Aloum L, Menon V, Al-Tel TH. El-Awady R, et al. Among authors: menon v. Bioorg Med Chem. 2021 Jul 15;42:116251. doi: 10.1016/j.bmc.2021.116251. Epub 2021 Jun 8. Bioorg Med Chem. 2021. PMID: 34116381

9

Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?

Lozon L, Saleh E, Menon V, Ramadan WS, Amin A, El-Awady R. Lozon L, et al. Among authors: menon v. Front Pharmacol. 2022 Sep 2;13:938471. doi: 10.3389/fphar.2022.938471. eCollection 2022. Front Pharmacol. 2022. PMID: 36120345 Free PMC article.

10

Mass spectroscopy-based proteomics and metabolomics analysis of triple-positive breast cancer cells treated with tamoxifen and/or trastuzumab.

Sharaf BM, Giddey AD, Al-Hroub HM, Menon V, Okendo J, El-Awady R, Mousa M, Almehdi A, Semreen MH, Soares NC. Sharaf BM, et al. Among authors: menon v. Cancer Chemother Pharmacol. 2022 Dec;90(6):467-488. doi: 10.1007/s00280-022-04478-4. Epub 2022 Oct 20. Cancer Chemother Pharmacol. 2022. PMID: 36264351

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