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Page 1
Improvement of islet transplantation by the fusion of islet cells with functional blood vessels.
Nalbach L, Roma LP, Schmitt BM, Becker V, Körbel C, Wrublewsky S, Pack M, Später T, Metzger W, Menger MM, Frueh FS, Götz C, Lin H, Manning Fox JE, MacDonald PE, Menger MD, Laschke MW, Ampofo E. Nalbach L, et al. Among authors: macdonald pe. EMBO Mol Med. 2021 Jan 11;13(1):e12616. doi: 10.15252/emmm.202012616. Epub 2020 Nov 2. EMBO Mol Med. 2021. PMID: 33135383 Free PMC article.
The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.
Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13. Diabetologia. 2012. PMID: 22411134
Functional plasticity of the human infant β-cell exocytotic phenotype.
Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AM, Korbutt G, MacDonald PE. Fox JE, et al. Among authors: macdonald pe. Endocrinology. 2013 Apr;154(4):1392-9. doi: 10.1210/en.2012-1934. Epub 2013 Feb 28. Endocrinology. 2013. PMID: 23449893
Human islet function following 20 years of cryogenic biobanking.
Manning Fox JE, Lyon J, Dai XQ, Wright RC, Hayward J, van de Bunt M, Kin T, Shapiro AM, McCarthy MI, Gloyn AL, Ungrin MD, Lakey JR, Kneteman NM, Warnock GL, Korbutt GS, Rajotte RV, MacDonald PE. Manning Fox JE, et al. Among authors: macdonald pe. Diabetologia. 2015 Jul;58(7):1503-12. doi: 10.1007/s00125-015-3598-4. Epub 2015 May 1. Diabetologia. 2015. PMID: 25930156 Free PMC article.
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Chakravarthy H, Gu X, Enge M, Dai X, Wang Y, Damond N, Downie C, Liu K, Wang J, Xing Y, Chera S, Thorel F, Quake S, Oberholzer J, MacDonald PE, Herrera PL, Kim SK. Chakravarthy H, et al. Among authors: macdonald pe. Cell Metab. 2017 Mar 7;25(3):622-634. doi: 10.1016/j.cmet.2017.01.009. Epub 2017 Feb 16. Cell Metab. 2017. PMID: 28215845 Free PMC article.
Metabolomics applied to islet nutrient sensing mechanisms.
Jensen MV, Gooding JR, Ferdaoussi M, Dai XQ, Peterson BS, MacDonald PE, Newgard CB. Jensen MV, et al. Among authors: macdonald pe. Diabetes Obes Metab. 2017 Sep;19 Suppl 1(Suppl 1):90-94. doi: 10.1111/dom.13010. Diabetes Obes Metab. 2017. PMID: 28880482 Free PMC article. Review.
Cystic fibrosis-related diabetes is caused by islet loss and inflammation.
Hart NJ, Aramandla R, Poffenberger G, Fayolle C, Thames AH, Bautista A, Spigelman AF, Babon JAB, DeNicola ME, Dadi PK, Bush WS, Balamurugan AN, Brissova M, Dai C, Prasad N, Bottino R, Jacobson DA, Drumm ML, Kent SC, MacDonald PE, Powers AC. Hart NJ, et al. Among authors: macdonald pe. JCI Insight. 2018 Apr 19;3(8):e98240. doi: 10.1172/jci.insight.98240. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669939 Free PMC article.
β Cell tone is defined by proglucagon peptides through cAMP signaling.
Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. Capozzi ME, et al. Among authors: macdonald pe. JCI Insight. 2019 Mar 7;4(5):e126742. doi: 10.1172/jci.insight.126742. eCollection 2019 Mar 7. JCI Insight. 2019. PMID: 30720465 Free PMC article.
157 results