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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.
Prague JK, Roberts RE, Comninos AN, Clarke S, Jayasena CN, Nash Z, Doyle C, Papadopoulou DA, Bloom SR, Mohideen P, Panay N, Hunter MS, Veldhuis JD, Webber LC, Huson L, Dhillo WS. Prague JK, et al. Lancet. 2017 May 6;389(10081):1809-1820. doi: 10.1016/S0140-6736(17)30823-1. Epub 2017 Apr 3. Lancet. 2017. PMID: 28385352 Free PMC article. Clinical Trial.
Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy.
Abbara A, Jayasena CN, Christopoulos G, Narayanaswamy S, Izzi-Engbeaya C, Nijher GM, Comninos AN, Peters D, Buckley A, Ratnasabapathy R, Prague JK, Salim R, Lavery SA, Bloom SR, Szigeti M, Ashby DA, Trew GH, Dhillo WS. Abbara A, et al. Among authors: prague jk. J Clin Endocrinol Metab. 2015 Sep;100(9):3322-31. doi: 10.1210/jc.2015-2332. Epub 2015 Jul 20. J Clin Endocrinol Metab. 2015. PMID: 26192876 Free PMC article. Clinical Trial.
Potential Clinical Use of Kisspeptin.
Prague JK, Dhillo WS. Prague JK, et al. Neuroendocrinology. 2015;102(3):238-45. doi: 10.1159/000439133. Epub 2015 Aug 7. Neuroendocrinology. 2015. PMID: 26277870 Review.
Subcutaneous infusion of kisspeptin-54 stimulates gonadotrophin release in women and the response correlates with basal oestradiol levels.
Narayanaswamy S, Jayasena CN, Ng N, Ratnasabapathy R, Prague JK, Papadopoulou D, Abbara A, Comninos AN, Bassett P, Bloom SR, Veldhuis JD, Dhillo WS. Narayanaswamy S, et al. Among authors: prague jk. Clin Endocrinol (Oxf). 2016 Jun;84(6):939-45. doi: 10.1111/cen.12977. Epub 2015 Dec 17. Clin Endocrinol (Oxf). 2016. PMID: 26572695 Free PMC article. Clinical Trial.
Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men.
Narayanaswamy S, Prague JK, Jayasena CN, Papadopoulou DA, Mizamtsidi M, Shah AJ, Bassett P, Comninos AN, Abbara A, Bloom SR, Veldhuis JD, Dhillo WS. Narayanaswamy S, et al. Among authors: prague jk. J Clin Endocrinol Metab. 2016 Sep;101(9):3429-36. doi: 10.1210/jc.2016-1911. Epub 2016 Jul 5. J Clin Endocrinol Metab. 2016. PMID: 27379743 Free PMC article.
30 results