Beutler JA - Search Results

1

Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H.

Tocco G, Esposito F, Caboni P, Laus A, Beutler JA, Wilson JA, Corona A, Le Grice SFJ, Tramontano E. Tocco G, et al. Among authors: beutler ja. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1953-1963. doi: 10.1080/14756366.2020.1835884. J Enzyme Inhib Med Chem. 2020. PMID: 33143469 Free PMC article.

2

High throughput screening for cyanovirin-N mimetics binding to HIV-1 gp41.

Beutler JA, McMahon JB, Johnson TR, O'Keefe BR, Buzzell RA, Robbins D, Gardella R, Wilson J, Boyd MR. Beutler JA, et al. J Biomol Screen. 2002 Apr;7(2):105-10. doi: 10.1177/108705710200700202. J Biomol Screen. 2002. PMID: 12006108

3

A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity.

Parniak MA, Min KL, Budihas SR, Le Grice SF, Beutler JA. Parniak MA, et al. Among authors: beutler ja. Anal Biochem. 2003 Nov 1;322(1):33-9. doi: 10.1016/j.ab.2003.06.001. Anal Biochem. 2003. PMID: 14705777

4

A capillary electrophoretic assay for ribonuclease H activity.

Chan KC, Budihas SR, Le Grice SF, Parniak MA, Crouch RJ, Gaidamakov SA, Isaaq HJ, Wamiru A, McMahon JB, Beutler JA. Chan KC, et al. Among authors: beutler ja. Anal Biochem. 2004 Aug 15;331(2):296-302. doi: 10.1016/j.ab.2004.05.017. Anal Biochem. 2004. PMID: 15265735

5

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.

Budihas SR, Gorshkova I, Gaidamakov S, Wamiru A, Bona MK, Parniak MA, Crouch RJ, McMahon JB, Beutler JA, Le Grice SF. Budihas SR, et al. Among authors: beutler ja. Nucleic Acids Res. 2005 Mar 1;33(4):1249-56. doi: 10.1093/nar/gki268. Print 2005. Nucleic Acids Res. 2005. PMID: 15741178 Free PMC article.

6

A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H.

Dat NT, Bae K, Wamiru A, McMahon JB, Le Grice SF, Bona M, Beutler JA, Kim YH. Dat NT, et al. Among authors: beutler ja. J Nat Prod. 2007 May;70(5):839-41. doi: 10.1021/np060359m. Epub 2007 Mar 31. J Nat Prod. 2007. PMID: 17397219

7

An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis.

Takada K, Bermingham A, O'Keefe BR, Wamiru A, Beutler JA, Le Grice SF, Lloyd J, Gustafson KR, McMahon JB. Takada K, et al. Among authors: beutler ja. J Nat Prod. 2007 Oct;70(10):1647-9. doi: 10.1021/np0702279. Epub 2007 Oct 13. J Nat Prod. 2007. PMID: 17935297

8

Madurahydroxylactone derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and RNase H.

Marchand C, Beutler JA, Wamiru A, Budihas S, Möllmann U, Heinisch L, Mellors JW, Le Grice SF, Pommier Y. Marchand C, et al. Among authors: beutler ja. Antimicrob Agents Chemother. 2008 Jan;52(1):361-4. doi: 10.1128/AAC.00883-07. Epub 2007 Oct 29. Antimicrob Agents Chemother. 2008. PMID: 17967911 Free PMC article.

9

HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.

Bokesch HR, Wamiru A, Le Grice SF, Beutler JA, McKee TC, McMahon JB. Bokesch HR, et al. Among authors: beutler ja. J Nat Prod. 2008 Sep;71(9):1634-6. doi: 10.1021/np8002518. Epub 2008 Sep 3. J Nat Prod. 2008. PMID: 18763827 Free PMC article.

10

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity.

Wendeler M, Lee HF, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler J, O'Keefe BR, Götte M, Kvaratskhelia M, Le Grice S. Wendeler M, et al. ACS Chem Biol. 2008 Oct 17;3(10):635-44. doi: 10.1021/cb8001039. Epub 2008 Oct 3. ACS Chem Biol. 2008. PMID: 18831589 Free PMC article.

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