Işbilir A - Search Results

1

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.

Işbilir A, Möller J, Arimont M, Bobkov V, Perpiñá-Viciano C, Hoffmann C, Inoue A, Heukers R, de Graaf C, Smit MJ, Annibale P, Lohse MJ. Işbilir A, et al. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29144-29154. doi: 10.1073/pnas.2013319117. Epub 2020 Nov 4. Proc Natl Acad Sci U S A. 2020. PMID: 33148803 Free PMC article.

2

Kinetic Analysis of the Early Signaling Steps of the Human Chemokine Receptor CXCR4.

Perpiñá-Viciano C, Işbilir A, Zarca A, Caspar B, Kilpatrick LE, Hill SJ, Smit MJ, Lohse MJ, Hoffmann C. Perpiñá-Viciano C, et al. Among authors: isbilir a. Mol Pharmacol. 2020 Aug;98(2):72-87. doi: 10.1124/mol.119.118448. Epub 2020 May 30. Mol Pharmacol. 2020. PMID: 32474443 Free PMC article.

3

Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3.

Heuninck J, Perpiñá Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C. Heuninck J, et al. Among authors: isbilir a. Mol Pharmacol. 2019 Dec;96(6):778-793. doi: 10.1124/mol.118.115477. Epub 2019 May 15. Mol Pharmacol. 2019. PMID: 31092552 Free article. Review.

4

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.

Möller J, Isbilir A, Sungkaworn T, Osberg B, Karathanasis C, Sunkara V, Grushevskyi EO, Bock A, Annibale P, Heilemann M, Schütte C, Lohse MJ. Möller J, et al. Among authors: isbilir a. Nat Chem Biol. 2020 Sep;16(9):946-954. doi: 10.1038/s41589-020-0566-1. Epub 2020 Jun 15. Nat Chem Biol. 2020. PMID: 32541966

5

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.

Işbilir A, Serfling R, Möller J, Thomas R, De Faveri C, Zabel U, Scarselli M, Beck-Sickinger AG, Bock A, Coin I, Lohse MJ, Annibale P. Işbilir A, et al. Nat Protoc. 2021 Mar;16(3):1419-1451. doi: 10.1038/s41596-020-00458-1. Epub 2021 Jan 29. Nat Protoc. 2021. PMID: 33514946

6

A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H₃ Receptor.

Rosier N, Grätz L, Schihada H, Möller J, Işbilir A, Humphrys LJ, Nagl M, Seibel U, Lohse MJ, Pockes S. Rosier N, et al. Among authors: isbilir a. J Med Chem. 2021 Aug 12;64(15):11695-11708. doi: 10.1021/acs.jmedchem.1c01089. Epub 2021 Jul 26. J Med Chem. 2021. PMID: 34309390

7

Structural and Functional Characterization of Allatostatin Receptor Type-C of Thaumetopoea pityocampa, a Potential Target for Next-Generation Pest Control Agents.

Shahraki A, Işbilir A, Dogan B, Lohse MJ, Durdagi S, Birgul-Iyison N. Shahraki A, et al. Among authors: isbilir a. J Chem Inf Model. 2021 Feb 22;61(2):715-728. doi: 10.1021/acs.jcim.0c00985. Epub 2021 Jan 21. J Chem Inf Model. 2021. PMID: 33476150

8

Pharmacological Characterization of the Stick Insect Carausius morosus Allatostatin-C Receptor with Its Endogenous Agonist.

Işbilir A, Duan Sahbaz B, Tuncgenc G, Bünemann M, Lohse MJ, Birgül-Iyison N. Işbilir A, et al. ACS Omega. 2020 Dec 8;5(50):32183-32194. doi: 10.1021/acsomega.0c03382. eCollection 2020 Dec 22. ACS Omega. 2020. PMID: 33376856 Free PMC article.

9

Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB₁R) "Cis-On" Agonist.

Rodríguez-Soacha DA, Steinmüller SAM, Işbilir A, Fender J, Deventer MH, Ramírez YA, Tutov A, Sotriffer C, Stove CP, Lorenz K, Lohse MJ, Hislop JN, Decker M. Rodríguez-Soacha DA, et al. Among authors: isbilir a. ACS Chem Neurosci. 2022 Aug 17;13(16):2410-2435. doi: 10.1021/acschemneuro.2c00160. Epub 2022 Jul 26. ACS Chem Neurosci. 2022. PMID: 35881914

10

ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.

Aydin A, Klenk C, Nemec K, Işbilir A, Martin LM, Zauber H, Rrustemi T, Toka HR, Schuster H, Gong M, Stricker S, Bock A, Bähring S, Selbach M, Lohse MJ, Luft FC. Aydin A, et al. Among authors: isbilir a. Life Sci Alliance. 2024 Feb 8;7(4):e202302400. doi: 10.26508/lsa.202302400. Print 2024 Apr. Life Sci Alliance. 2024. PMID: 38331475 Free PMC article.

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