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The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function.
Mapperley C, van de Lagemaat LN, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J, Sarapuu A, Choe J, Ivanova I, Krause DS, von Kriegsheim A, Much C, Morgan M, Gregory RI, Mead AJ, O'Carroll D, Kranc KR. Mapperley C, et al. Among authors: von kriegsheim a. J Exp Med. 2021 Mar 1;218(3):e20200829. doi: 10.1084/jem.20200829. J Exp Med. 2021. PMID: 33156926 Free PMC article.
Towards complete analysis of the platelet proteome.
O'Neill EE, Brock CJ, von Kriegsheim AF, Pearce AC, Dwek RA, Watson SP, Hebestreit HF. O'Neill EE, et al. Among authors: von kriegsheim af. Proteomics. 2002 Mar;2(3):288-305. doi: 10.1002/1615-9861(200203)2:3<288::aid-prot288>3.0.co;2-0. Proteomics. 2002. PMID: 11921445
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Hooftman A, Peace CG, Ryan DG, Day EA, Yang M, McGettrick AF, Yin M, Montano EN, Huo L, Toller-Kawahisa JE, Zecchini V, Ryan TAJ, Bolado-Carrancio A, Casey AM, Prag HA, Costa ASH, De Los Santos G, Ishimori M, Wallace DJ, Venuturupalli S, Nikitopoulou E, Frizzell N, Johansson C, Von Kriegsheim A, Murphy MP, Jefferies C, Frezza C, O'Neill LAJ. Hooftman A, et al. Among authors: von kriegsheim a. Nature. 2023 Mar;615(7952):490-498. doi: 10.1038/s41586-023-05720-6. Epub 2023 Mar 8. Nature. 2023. PMID: 36890227 Free PMC article.
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species.
Martín-Vega A, Ruiz-Peinado L, García-Gómez R, Herrero A, de la Fuente-Vivas D, Parvathaneni S, Caloto R, Morante M, von Kriegsheim A, Bustelo XR, Sacks DB, Casar B, Crespo P. Martín-Vega A, et al. Among authors: von kriegsheim a. Sci Adv. 2023 Feb 15;9(7):eadd7969. doi: 10.1126/sciadv.add7969. Epub 2023 Feb 15. Sci Adv. 2023. PMID: 36791195 Free PMC article.
MYC sensitises cells to apoptosis by driving energetic demand.
Edwards-Hicks J, Su H, Mangolini M, Yoneten KK, Wills J, Rodriguez-Blanco G, Young C, Cho K, Barker H, Muir M, Guerrieri AN, Li XF, White R, Manasterski P, Mandrou E, Wills K, Chen J, Abraham E, Sateri K, Qian BZ, Bankhead P, Arends M, Gammoh N, von Kriegsheim A, Patti GJ, Sims AH, Acosta JC, Brunton V, Kranc KR, Christophorou M, Pearce EL, Ringshausen I, Finch AJ. Edwards-Hicks J, et al. Among authors: von kriegsheim a. Nat Commun. 2022 Aug 9;13(1):4674. doi: 10.1038/s41467-022-32368-z. Nat Commun. 2022. PMID: 35945217 Free PMC article.
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function.
Sun C, De Mello V, Mohamed A, Ortuste Quiroga HP, Garcia-Munoz A, Al Bloshi A, Tremblay AM, von Kriegsheim A, Collie-Duguid E, Vargesson N, Matallanas D, Wackerhage H, Zammit PS. Sun C, et al. Among authors: von kriegsheim a. Stem Cells. 2017 Aug;35(8):1958-1972. doi: 10.1002/stem.2652. Epub 2017 Jun 27. Stem Cells. 2017. PMID: 28589555 Free PMC article.
140 results